Related Experiment Video
Updated: Jun 12, 2026

Antibiotic Dereplication Using the Antibiotic Resistance Platform
Published on: October 17, 2019
Molding national research systems: the introduction of penicillin to Germany and France
Jean-Paul Gaudillière1, Bernd Gausemeier
1Institut National de la Santé et de la Recherche Médicale, Paris, France. gaudilli@ext.jussieu.fr
Abstract:
In our historical imagination, penicillin plays the role of the good sister of the atomic bomb. It epitomizes the success of the U.S. scientific mobilization and the emergence of modem biomedicine. This chapter discusses the fate of penicillin in France and Germany, comparing the reactions of the two countries to the antibiotic challenge under restricted conditions. The comparison centers on the scientific and industrial practices that created penicillin. It also sheds light on the professional styles, forms of expertise, and political resources that helped shape the meanings and uses of the antibiotic. The French section recounts how the Pasteur Institute and the military administration organized penicillin research and production during 1945-1947. The alliance between the two has roots in the highly peculiar political and social climate of the liberation and in the biotechnological tradition of the Pasteur Institute. The German section focuses on the Kaiser Wilhelm Institute for Biochemistry. The study of the institute, which worked closely with a pharmaceutical company, features the interplay between academic chemists and industry, while providing insights into the research organization under National Socialism.
Related Concept Videos
Production of Antibiotics
History of Microbiology
Microorganisms in Medicine and Therapeutics
Mechanism of Antibiotic Resistance in MRSA
Inhibitors of Gram-positive Cell Wall Synthesis
Clinical Significance of Antibiotic Resistance
