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Family distances as a measure of hidden consanguinity. A reappraisal
J Swaving1, A Groenewegen, A Kamstra
1Department of Medical Genetics, University of Groningen, The Netherlands.
Human Heredity
|January 1, 1991
Abstract:
We compared the family distances of patients with autosomal recessive disorders with those of a random control group and a matched control group. Only in the great-grandparental generation were weak-significant differences found. We also found that the family distances of persons with an urban origin were significantly larger than those of persons with a rural origin. In our study, family distance seems to be a more powerful measure of hidden consanguinity than the parental distance.