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Updated: Jun 12, 2026
Matrix-assisted Autologous Chondrocyte Transplantation for Remodeling and Repair of Chondral Defects in a Rabbit Model
Published on: May 21, 2013
Autologous matrix-induced chondrogenesis (AMIC). A one-step procedure for retropatellar articular resurfacing
Jan Philipp Benthien1, Peter Behrens
1Hip, Knee and Endoprosthetic Division, Department of Orthopaedic Surgery, Basel University Hospital, Basel, Switzerland. jbenthien@uhbs.ch
Abstract:
The objective of this technical note is to describe the autologous matrix induced chondrogenesis (AMIC) procedure and to evaluate its possible role for resurfacing of retropatellar cartilage defects. AMIC is a one-step procedure combining microfracturing with application of a collagen I/III membrane to protect the initial blood clot and to serve as a scaffold for the developing chondrocytes. A retrospective analysis of our experience in three patients followed for 18 months is presented.
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