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[Mechanical circulatory assist using a miniaturized Archimedes screw]
L K von Segesser1, B Bisang, B Leskosek
1Klinik für Herzgefässchirurgie, Universitätsspital Zürich.
Helvetica Chirurgica Acta
|January 1, 1991
Summary
This study compared an axial flow blood pump to standard left heart bypass in bovine models. The axial pump showed less blood trauma but lacked flow assessment, posing a management challenge.
Area of Science:
- Cardiovascular Surgery
- Biomedical Engineering
- Medical Devices
Background:
- Left ventricular assist devices (LVADs) are crucial for managing heart failure.
- Traditional left heart bypass (LHBP) using roller pumps has limitations.
- Novel pump designs, like axial flow pumps, require thorough evaluation.
Purpose of the Study:
- To compare the performance and characteristics of an intraarterial axial flow blood pump against standard roller pump LHBP.
- To assess potential advantages and disadvantages of the axial flow pump in a preclinical setting.
Main Methods:
- Thirteen bovine experiments were conducted, comparing an axial flow pump to a roller pump LHBP.
- Limited systemic heparinization was used for the axial pump (ACT > 180 s) versus full heparinization for LHBP (ACT > 500 s).
- A standard battery of blood samples was collected pre- and post-perfusion.
Main Results:
- The axial flow blood pump demonstrated transarterial access and reduced blood trauma compared to LHBP.
- Key advantages included less invasive access and minimized damage to blood components.
- A significant drawback identified was the inability to directly assess pump flow, complicating management.
Conclusions:
- The axial flow blood pump offers benefits in terms of access and blood compatibility.
- The lack of flow monitoring capability presents a critical challenge for clinical application in failing left ventricles.
- Further development is needed to incorporate flow measurement for effective use.