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Related Concept Videos

Development of the Lymphatic System01:15

Development of the Lymphatic System

The development of lymphatic tissues and vessels in embryonic life begins around the fifth week. These structures originate from the mesoderm layer, with lymph sacs emerging from developing veins.
The first lymph sacs to form are the paired jugular lymph sacs located at the junction of the internal jugular and subclavian veins. From these sacs, lymphatic capillary plexuses extend to the thorax, upper limbs, neck, and head, eventually forming lymphatic vessels. Each jugular lymph sac maintains a...
Lymphatic Vessels and Lymph Transport01:16

Lymphatic Vessels and Lymph Transport

Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells.
This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular spaces.
Introduction to Lymphatic and Immune System01:23

Introduction to Lymphatic and Immune System

Immunity is a crucial biological concept about our body's inherent capacity to prevent infections and diseases. A complex network of cells and tissues collectively known as the immune system facilitates this natural defense mechanism. The immune system plays an integral role in maintaining our health and well-being, shielding us from potential health threats.
The immune responses can be categorized into two types: innate and adaptive. Innate immunity comprises nonspecific defenses we are born...
Functions of the Lymphatic and Immune System01:28

Functions of the Lymphatic and Immune System

The lymphatic system plays a crucial role in bolstering our immune system. It consists of a network of lymphoid organs, lymph, and lymphatic vessels that provide structural and functional support in safeguarding the body against pathogens such as viruses and bacteria.
The primary lymphoid organs, including the bone marrow and the thymus, serve as the maturation sites for lymphocytes. Secondary lymphoid organs, like the mucosa-associated lymphoid tissue, activate these lymphocytes and serve as...
Detailed Structure and Function of Lymph Nodes01:23

Detailed Structure and Function of Lymph Nodes

Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
Cytotoxic Edema: Pathophysiology01:21

Cytotoxic Edema: Pathophysiology

Cytotoxic edema is a form of cerebral edema characterized by intracellular swelling of neurons, astrocytes, and other glial cells. It develops when the mechanisms responsible for maintaining ionic gradients across the cell membrane become impaired. Under normal physiological conditions, the sodium–potassium ATPase actively transports sodium ions out of the cell and potassium ions into the cell, preserving osmotic balance and enabling electrical signaling. This pump requires a continuous supply...

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Related Experiment Video

Updated: Jun 12, 2026

A Murine Tail Lymphedema Model
04:38

A Murine Tail Lymphedema Model

Published on: February 10, 2021

Lymphoedema in children: an overview.

Marie Todd1

  • 1Lymphoedema Service, Greater Glasgow and Clyde NHS Trust, UK.

British Journal of Nursing (Mark Allen Publishing)
|May 28, 2010
PubMed
Summary

Pediatric lymphoedema is uncommon and often overlooked, leading to significant challenges for affected children in accessing care. Early referral to a lymphoedema specialist is crucial for managing this lifelong condition.

Area of Science:

  • Pediatric medicine
  • Vascular medicine
  • Genetics

Background:

  • Lymphoedema in children is a rare but serious condition.
  • Affected children face substantial barriers to accessing appropriate healthcare services and treatments.
  • The long-term global impact of pediatric lymphoedema is frequently underestimated.

Purpose of the Study:

  • To outline the causes, effects, and treatment of pediatric lymphoedema.
  • To emphasize the need for specialized care for children with this condition.
  • To provide recommendations for improving management strategies.

Main Methods:

  • Literature review on pediatric lymphoedema.
  • Analysis of current service provision and treatment outcomes.
  • Synthesis of expert recommendations for clinical practice.

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A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice
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A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice

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Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

Related Experiment Videos

Last Updated: Jun 12, 2026

A Murine Tail Lymphedema Model
04:38

A Murine Tail Lymphedema Model

Published on: February 10, 2021

A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice
09:50

A Revised Method for Inducing Secondary Lymphedema in the Hindlimb of Mice

Published on: November 2, 2019

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
07:36

Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting

Published on: May 1, 2015

Main Results:

  • Lymphoedema in children presents unique challenges due to its rarity and under-recognition.
  • Delayed diagnosis and inadequate treatment contribute to long-term morbidity.
  • Specialized lymphoedema services are essential for effective management.

Conclusions:

  • All children diagnosed with lymphoedema require prompt referral to a lymphoedema specialist.
  • Early intervention can mitigate the long-term consequences of the condition.
  • Increased awareness and improved access to specialized care are vital for pediatric patients.