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Updated: Jun 12, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation

Published on: February 28, 2012

[ICD therapy as secondary prevention].

K Seidl¹, M Strauss, T Kleemann

¹Zentrum für Herzrhythmusstörungen Ludwigshafen, Bremserstr. 79, 67063, Ludwigshafen, Deutschland. seidlk@klilu.de

Herzschrittmachertherapie & Elektrophysiologie

|May 28, 2010

Summary

Implantable cardioverter defibrillators (ICDs) reduce mortality by 28% in patients at high risk of sudden cardiac death. ICDs are most effective for unstable ventricular tachycardia, with benefits for older patients needing further study.

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Last Updated: Jun 12, 2026

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation

A New Single Chamber Implantable Defibrillator with Atrial Sensing: A Practical Demonstration of Sensing and Ease of Implantation

Published on: February 28, 2012

Area of Science:

Cardiology
Electrophysiology
Preventive Medicine

Background:

Patients surviving out-of-hospital cardiac arrest face high recurrence risk.
Implantable cardioverter defibrillators (ICDs) offer secondary prevention for ventricular tachyarrhythmias (VT).

Purpose of the Study:

To review key clinical trials on ICDs for secondary prevention of sudden cardiac death.
To evaluate ICD effectiveness in diverse patient subgroups.

Main Methods:

Meta-analysis of clinical trials on ICDs for secondary prevention.
Review of data regarding ICD efficacy in patients with stable versus unstable VT.
Analysis of existing data on ICDs in older adult populations.

Main Results:

Meta-analysis revealed a 28% relative risk reduction in overall mortality with ICDs.
ICDs showed maximal benefit in patients with ejection fraction 20-35% compared to amiodarone.
ICD effectiveness is clear for unstable VT, less so for stable VT; data for older patients is limited.

Conclusions:

ICDs are effective for secondary prevention in patients with unstable VT.
Further research is needed on ICD safety, effectiveness, and cost-effectiveness in older populations.
Individualized patient-physician dialogue is crucial for ICD implantation decisions.