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In Vivo Assessment of Rodent Plasmodium Parasitemia and Merozoite Invasion by Flow Cytometry
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Cytometry in malaria: from research tool to practical diagnostic approach?

Howard M Shapiro1, Henning Ulrich

  • 1The Center for Microbial Cytometry and Howard M. Shapiro, M.D., P.C., 283 Highland Avenue, West Newton, Massachusetts 02465-2513, USA. hms@shapirolab.com

Cytometry. Part a : the Journal of the International Society for Analytical Cytology
|May 28, 2010
PubMed
Summary

No abstract available in PubMed .

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Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...

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