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Updated: Jun 12, 2026

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
[Chemical constituents in Flos Sophorae Carbonisatus]
Raorao Li1, Caifang Wang, Peilin Lei
1Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China. leeraorao@163.com
Objective:
To investigate the chemical constituents of lipid-soluble and water-soluble extracts in Flos Sophorae Carbonisatus.
Method:
The compounds were isolated by means of solvent extraction and column chromatography, and their structures were determined by spectral analysis.
Result:
Two compounds from petroleum ether extract and ten from n-BuOH extract were isolated and identified as sophoradiol (1), beta-sitosterol (2), 3 beta, 22 beta, 24-trihydroxy-olean-12-ene (soyasapogenol B) (3), daucosterol (4), kaikasaponin I (5), quercetin (6), isorhamnetin (7), 2-O-methyl-insitol (8), isorhamnetin-3-O-rutinoside (9), isoquercitrin (10), orobol-7-O-beta-D-glucoside (11), rutin (12), respectively.
Conclusion:
Compound 3, 8-11 were isolated from Flos Sophorae Carbonisatus for the first time. The results could be basic foundation for further study on processing mechanism of Flos Sophorae Carbonisatus.
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