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Updated: Jun 12, 2026

Characterization of Vascular Morphology of Neovascular Age-Related Macular Degeneration by Indocyanine Green Angiography
Published on: August 11, 2023
Compassionate use of intravitreal pegaptanib in patients with age-related macular degeneration
Federico Ricci1, Filippo Missiroli, Claudio Cedrone
1Università degli Studi di Roma "Tor Vergata" Unità Operativa Dipartimentale Patologie Retiniche Policlinico "Tor Vergata," Rome, Italy.
Abstract:
The study aim was to evaluate the short-term safety and efficacy of pegaptanib sodium injections (Macugen, Eyetech Pharmaceuticals, Inc., New York, NY) in the compassionate-use therapy of choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD). Intravitreal pegaptanib was used to treat 41 eyes in 40 patients with CNV. Injections were given every 6 weeks, and a minimum of three injections were planned. The mean change in BCVA for all lesions was a loss of 0.03 Snellen lines. Seven eyes (17.1%) gained more than 3 lines, three (7.31%) lost 6 lines or more, and in 75.6% the BCVA stabilized or improved.
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