Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 12, 2026

A Simplified Protocol for Protecting Palatal Soft Tissue Donor Sites Using an Oral Mucoadhesive Bandage

A Simplified Protocol for Protecting Palatal Soft Tissue Donor Sites Using an Oral Mucoadhesive Bandage

Published on: February 17, 2026

Sutureless patch graft for sterile corneal melts.

Noopur Gupta¹, Ritika Sachdev, Radhika Tandon

¹All India Institute of Medical Sciences, New Delhi, Delhi, India.

|May 29, 2010

Summary

A novel technique uses a corneal graft and biological glue to seal large sterile corneal melts, avoiding sutures and emergency surgery. This method provides tectonic support and improves vision in affected patients.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Management of retinoblastoma during the Covid-19 pandemic: Experience at a tertiary care centre.

The National medical journal of India·2026

Same author

Sex differences in congenital hereditary endothelial dystrophy (CHED) and Slc4a11<sup>-/-</sup> mouse model of CHED.

Biology of sex differences·2026

Same author

"Best Pick and Hold" with "Wrap and Roll" technique for extreme subluxated crystalline lens.

Indian journal of ophthalmology·2026

Same author

Smartphone applications as assistive technology for the visually impaired individuals: A hospital-based cross-sectional study.

Indian journal of ophthalmology·2026

Same author

Corneal biomechanics with CORVIS-ST in post-keratoplasty corneas.

Indian journal of ophthalmology·2026

Same author

Microbiological profile and antibiotic resistance trends of preoperative conjunctival swabs: An 8-year retrospective analysis from a North Indian tertiary care ophthalmic center.

Indian journal of ophthalmology·2025

Area of Science:

Ophthalmology
Corneal Surgery
Tissue Adhesives

Background:

Large paracentral corneal melts pose a significant challenge in ophthalmology.
Traditional treatments often involve sutures or emergency penetrating keratoplasty.

Observation:

Two patients with sterile corneal melts (3-5 mm) were treated.
A full-thickness patch graft, prepared with a dermatological trephine, was used.

Findings:

The graft was secured using fibrin-aprotinin biological tissue adhesive, eliminating the need for sutures.
The corneal defects were effectively sealed, providing tectonic support.
Postoperative best-corrected visual acuity improved to 6/24 in both patients.

Implications:

More Related Videos

Corneal Donor Tissue Preparation for Endothelial Keratoplasty

Corneal Donor Tissue Preparation for Endothelial Keratoplasty

Published on: June 12, 2012

Related Experiment Videos

Last Updated: Jun 12, 2026

A Simplified Protocol for Protecting Palatal Soft Tissue Donor Sites Using an Oral Mucoadhesive Bandage

A Simplified Protocol for Protecting Palatal Soft Tissue Donor Sites Using an Oral Mucoadhesive Bandage

Published on: February 17, 2026

Corneal Donor Tissue Preparation for Endothelial Keratoplasty

Corneal Donor Tissue Preparation for Endothelial Keratoplasty

Published on: June 12, 2012

This sutureless technique offers a viable alternative for managing large corneal melts.
It potentially avoids the risks and complications associated with emergency penetrating keratoplasty.
Successful visual outcomes suggest broader applicability in corneal reconstructive surgery.