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Published on: September 20, 2018
Infectious crystalline keratopathy caused by Streptococcus Abiotrophia defectiva
Florence Abry1, Arnaud Sauer, Philippe Riegel
1Department of Ophthalmology, University Hospital of Strasbourg, Strasbourg, France. florence.abry@chru-strasbourg.fr
Purpose:
To report the first case of Streptococcus Abiotrophia defectiva-associated crystalline keratopathy.
Methods:
An 83-year-old woman underwent penetrating keratoplasty for pseudophakic bullous keratopathy in the OD. Ten months after surgery, the patient presented with decreased visual acuity in the OD. Slit-lamp examination showed crystalline keratopathy. Corneal scrapings were negative, and the patient was treated empirically with 2 fortified antibiotics (ciprofloxacin and vancomycin). Despite these treatments, the surface of the infiltrate increased and corneal regrafting was performed 6 weeks later. The excised prior graft was evaluated microbiologically [culture and polymerase chain reaction (PCR)] and histopathologically.
Results:
In the explanted corneal graft, cultures grew Streptococcus A. defectiva, and its DNA was demonstrated by broad-range PCR (16S ribosomal DNA).
Conclusions:
A. defectiva can be a causative organism of infectious crystalline keratopathy. Risk factors may include long-term corticosteroid use and prior corneal transplantation. The present case confirms that PCR can be a useful technique in the diagnosis of deep infectious keratitis.
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