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Updated: Jun 12, 2026

Advanced Diffusion Imaging in The Hippocampus of Rats with Mild Traumatic Brain Injury
Published on: August 14, 2019
[Diffusion-weighted MR imaging of the brain]
O Naggara1, L Létourneau-Guillon, C Mellerio
1Unité de Recherche en Neuroradiologie Interventionnelle, Département de Radiologie, Centre hospitalier de l'Université de Montréal, Hôpital Notre-Dame, Montréal, Canada. o.naggara@ch-sainte-anne.fr
Abstract:
Imaging of water diffusion or diffusion-weighted MR imaging provides physiological information about brain diseases that cannot be obtained from conventional sequences. This technique is very sensitive for the detection of cerebral ischemia from arterial origin and can distinguish cerebral ischemia from other non-vascular brain pathologies in patients presenting with abrupt onset of focal neurological deficit. Diffusion-weighted imaging is used for the evaluation of non-vascular diseases as well. Combined with conventional sequences, it is helpful to differentiate brain abscesses from necrotic tumors. Quantitative diffusion-weighted imaging provides additional information in the characterization of tumors or inflammatory, degenerative and metabolic lesions. Finally, diffusion-weighted imaging data also has prognostic value.
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