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Updated: Jun 12, 2026
05:39
A Neonatal BALB/c Mouse Model of Necrotizing Enterocolitis
Published on: November 30, 2021
Allergic enterocolitis presenting as recurrent necrotizing enterocolitis in preterm neonates
P Srinivasan1, M Brandler, A D'Souza
1Department of Pediatrics, New York Hospital Queens, Flushing, NY 11355, USA. pns9001@nyp.org
Summary
Allergic enterocolitis from cow's milk protein allergy can mimic necrotizing enterocolitis (NEC) in newborns. Early diagnosis and formula modification can successfully manage this rare condition, preventing recurrent symptoms like pneumatosis and bloody stools.
Area of Science:
- Neonatal Medicine
- Pediatric Allergy
- Gastroenterology
Background:
- Cow's milk protein allergy is a common food allergy in infants and children.
- Allergic enterocolitis is an uncommon entity that can mimic necrotizing enterocolitis (NEC).
- The incidence and prevalence of NEC-like allergic enterocolitis in neonates are not well-documented.
Observation:
- A neonate presented with recurrent symptoms mimicking NEC, including pneumatosis and bloody stools.
- These symptoms were associated with cow's milk protein allergy.
Findings:
- The case highlights the unusual recurrent presentation of milk protein-associated allergic enterocolitis mimicking NEC.
- Successful management was achieved through modification of the infant's milk formula.
Implications:
- This case underscores the importance of considering allergic enterocolitis in neonates presenting with NEC-like symptoms.
- Formula modification is a viable and effective treatment strategy for this condition.
- Further research is needed to establish the true incidence and prevalence of this entity in neonates.
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