Detecting artery occlusion and critical flow diminution in the case of an acute ischemic stroke--methodological
S Schreiber1, F Schreiber, M Glaser
1Department of Neurology, Otto-von-Guericke University, Magdeburg. stefanie.schreiber@med.ovgu.de
Insights
Diagnostic imaging for acute ischemic stroke has limitations. Color-coded duplex sonography (CCDS) effectively resolved methodological pitfalls in 17.2% of patients, aiding accurate diagnosis.
Area of Science:
- Neurology
- Radiology
- Vascular Imaging
Background:
- Acute ischemic stroke diagnosis relies on vascular imaging like CTA, MRA, and DSA.
- These methods have inherent physical and physiological limitations.
- Misleading results can lead to inappropriate or missed acute therapeutic interventions.
Observation:
- A retrospective analysis of 269 acute stroke patients was conducted.
- 232 ischemic stroke patients underwent various vascular emergency diagnostic methods.
- 76 patients received two or more vascular examination techniques.
Findings:
- Controversial results occurred in 20 patients, primarily concerning large artery occlusion detection and differentiation from low flow.
- Methodological pitfalls were most reliably resolved using color-coded duplex sonography (CCDS).
- Vascular constellations prone to misinterpretation were identified in 17.2% of ischemic stroke patients.
Implications:
- CCDS is a valuable tool for resolving diagnostic ambiguities in acute stroke.
- A multimodal imaging approach, including CCDS, is recommended for emergency stroke settings.
- Technique selection should be guided by evolving diagnostic findings to optimize patient care.
Purpose:
None of the vascular emergency diagnostic methods commonly used in the case of acute ischemic stroke, i. e. CTA, color-coded duplex sonography (CCDS), MRA, and DSA, is free of restrictions due to physical and physiological characteristics. As a result, misleading results initiating an inappropriate acute therapeutic intervention or hampering a promising one cannot be excluded. We aimed to assess the type and frequency of methodological pitfalls occurring in this situation.
Materials And Methods:
We retrospectively analyzed data of 269 consecutive patients admitted to our stroke unit with a clinical syndrome of an acute stroke. All patients underwent one or more vascular emergency diagnostic methods on a routine basis.
Results:
37 patients were excluded because of a final diagnosis other than ischemic stroke. 76 of 232 ischemic stroke patients underwent emergency diagnostic methods with two or more vascular examination techniques. Controversial results occurred in 20 patients and related to the detection and localization of large artery occlusion and its differentiation from a low/slow flow situation and the identification of critical cerebral flow diminution distal to large artery occlusion/severe stenosis. Methodological pitfalls were able to be most reliably resolved by CCDS. Within the whole cohort of ischemic stroke patients, vascular constellations susceptible to misinterpretation were diagnosed in 40 (17.2 %) patients.
Conclusion:
We recommend providing several techniques including CCDS in an emergency stroke setting and applying techniques with respect to diagnostic findings.
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