Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Long-term Depression

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.

Long-term Depression

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Botulinum toxin treatment of cephalalgia alopecia increases substance P and calcitonin gene-related peptide-containing cutaneous nerves in scalp.

Cephalalgia : an international journal of headache·2009

Same author

Pain relief and persistence of dysautonomic features in a patient with hemicrania continua responsive to botulinum toxin type A.

Cephalalgia : an international journal of headache·2009

Same author

Cephalalgic alopecia areata: a syndrome of neuralgiform head pain and hair loss responsive to botulinum A toxin injection.

Cephalalgia : an international journal of headache·2006

Same author

Cluster headache with short-lived visual symptoms.

Cephalalgia : an international journal of headache·2006

Same author

Secondary SUNCT due to intraorbital, metastatic bronchial carcinoid.

Cephalalgia : an international journal of headache·2005

Same author

How treatment priorities influence triptan preferences in clinical practice: perspectives of migraine sufferers, neurologists, and primary care physicians.

Current medical research and opinion·2005

Search research articles

Related Experiment Video

Updated: Jun 12, 2026

Modeling Neural Immune Signaling of Episodic and Chronic Migraine Using Spreading Depression In Vitro

Modeling Neural Immune Signaling of Episodic and Chronic Migraine Using Spreading Depression In Vitro

Published on: June 13, 2011

Clinical translation: targeting cortical spreading depression

Cephalalgia : an International Journal of Headache

|June 1, 2010

Summary

No abstract available in PubMed .

More Related Videos

Combining Imaging and Electrophysiology to Visualize and Record Spreading Depolarizations in Mice

Combining Imaging and Electrophysiology to Visualize and Record Spreading Depolarizations in Mice

Published on: October 4, 2024

Related Experiment Videos

Last Updated: Jun 12, 2026

Modeling Neural Immune Signaling of Episodic and Chronic Migraine Using Spreading Depression In Vitro

Modeling Neural Immune Signaling of Episodic and Chronic Migraine Using Spreading Depression In Vitro

Published on: June 13, 2011

Combining Imaging and Electrophysiology to Visualize and Record Spreading Depolarizations in Mice

Combining Imaging and Electrophysiology to Visualize and Record Spreading Depolarizations in Mice

Published on: October 4, 2024