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Published on: September 2, 2021
Pericardial disease: diagnosis and management
Masud H Khandaker1, Raul E Espinosa, Rick A Nishimura
1Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA.
Insights
This review addresses diagnostic and management challenges in pericardial diseases, including acute pericarditis and pericardial effusion. It synthesizes current evidence to guide clinical decision-making for various pericardial syndromes.
Area of Science:
- Cardiology
- Internal Medicine
Background:
- Pericardial diseases encompass acute pericarditis, effusion, tamponade, and constrictive pericarditis, with potential for chronicity.
- Structural abnormalities like absent pericardium or cysts are rare and typically asymptomatic.
- Clinicians face complex questions regarding diagnosis, management, and treatment strategies for these conditions.
Purpose of the Study:
- To review current evidence and clinical experience for diagnosing and managing pericardial diseases.
- To provide guidance for clinicians on diagnostic criteria, tools, and treatment pathways.
- To address specific questions on hospitalization, medical management, corticosteroid use, and surgical intervention.
Main Methods:
- Literature search of PubMed and MEDLINE using keywords related to pericardial disease diagnosis and treatment.
- Selection of studies based on clinical relevance and impact on practice.
- Integration of institutional experience from a dedicated pericardial clinic.
Main Results:
- The review synthesizes available evidence to address key clinical questions.
- It offers practical guidance for managing diverse pericardial syndromes.
- Experiences from a specialized clinic inform the recommendations.
Conclusions:
- Effective diagnosis and management of pericardial diseases require a comprehensive understanding of current evidence.
- This review aims to equip clinicians with the knowledge to navigate diagnostic and therapeutic challenges.
- Evidence-based strategies are crucial for optimizing patient outcomes in pericardial disease management.
Abstract:
Pericardial diseases can present clinically as acute pericarditis, pericardial effusion, cardiac tamponade, and constrictive pericarditis. Patients can subsequently develop chronic or recurrent pericarditis. Structural abnormalities including congenitally absent pericardium and pericardial cysts are usually asymptomatic and are uncommon. Clinicians are often faced with several diagnostic and management questions relating to the various pericardial syndromes: What are the diagnostic criteria for the vast array of pericardial diseases? Which diagnostic tools should be used? Who requires hospitalization and who can be treated as an outpatient? Which medical management strategies have the best evidence base? When should corticosteroids be used? When should surgical pericardiectomy be considered? To identify relevant literature, we searched PubMed and MEDLINE using the keywords diagnosis, treatment, management, acute pericarditis, relapsing or recurrent pericarditis, pericardial effusion, cardiac tamponade, constrictive pericarditis, and restrictive cardiomyopathy. Studies were selected on the basis of clinical relevance and the impact on clinical practice. This review represents the currently available evidence and the experiences from the pericardial clinic at our institution to help guide the clinician in answering difficult diagnostic and management questions on pericardial diseases.
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