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Updated: Jun 12, 2026

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Pelvic exenteration for advanced and recurrent malignancy.

Evita Zoucas1, Sven Frederiksen, Marie-Louise Lydrup

  • 1Department of Surgery, University of Lund, Lund, Sweden. EZoucas@aol.com

World Journal of Surgery
|June 1, 2010
PubMed
Summary
This summary is machine-generated.

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Multivisceral pelvic resection is a viable option for advanced pelvic tumors, offering acceptable morbidity and improved quality of life (QoL). Careful patient selection and multimodal therapy are key to successful outcomes in complex cancer surgeries.

Area of Science:

  • Surgical Oncology
  • Pelvic Surgery
  • Cancer Treatment

Background:

  • Advanced pelvic tumors can be treated with curative intent using improved surgical techniques and oncological therapies.
  • Multivisceral pelvic resection is a complex procedure for advanced pelvic malignancies.
  • Evaluation of morbidity, survival, and quality of life (QoL) is crucial after extensive pelvic surgeries.

Purpose of the Study:

  • To assess the morbidity, survival rates, and quality of life (QoL) following multivisceral pelvic resection.
  • To determine the feasibility and outcomes of extended pelvic procedures for advanced pelvic tumors.

Main Methods:

  • Eighty-five patients underwent multivisceral pelvic resection between January 2003 and November 2008, with 87% having colorectal or anal malignancies.

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  • Procedures included total or posterior exenteration, with some involving partial cystectomy or bony pelvis resection. Reconstruction utilized myocutaneous flaps.
  • Preoperative multidisciplinary assessment, imaging, and often neoadjuvant chemotherapy and pelvic irradiation were employed. Urinary diversion methods included ileal conduit and continent pouch.

    • Main Results:

    • Sixty-six percent of patients achieved clear surgical margins. Median surgery duration was 680 minutes, with median blood loss of 1800 ml.
    • Overall morbidity was 68%, with major complications in 13%. Median hospital stay was 18 days. No 90-day mortality was observed.
    • Local control was achieved in 77 patients. Survival was correlated with clear margins and time to relapse. Quality of life (QoL) improved at 16 months post-surgery.

    Conclusions:

    • Multivisceral pelvic surgery can be performed with acceptable morbidity and improved quality of life (QoL).
    • Thorough patient selection is essential for maximizing the benefits of these extensive surgical procedures.
    • Multimodal therapy, including neoadjuvant treatments, plays a critical role in achieving optimal outcomes in advanced pelvic tumor resections.