Related Experiment Videos
Intestinal motility in symptomatic children with fundoplication
C Di Lorenzo1, A Flores, P E Hyman
1Department of Pediatrics, Harbor-UCLA Medical Center, Torrance, CA 90502.
Journal of Pediatric Gastroenterology and Nutrition
|February 1, 1991
Summary
Fundoplication did not improve severe gastrointestinal symptoms in children. Preoperative intestinal manometry may identify patients unlikely to benefit from this surgery.
Area of Science:
- Pediatric Gastroenterology
- Gastrointestinal Motility Disorders
Background:
- Fundoplication is a surgical procedure to treat severe gastroesophageal reflux.
- It alters lower esophageal sphincter anatomy but is not expected to affect distal motility.
- Persistent or worsening gastrointestinal symptoms after fundoplication suggest underlying motility issues.
Purpose of the Study:
- To investigate antroduodenal motility in children with persistent symptoms after fundoplication.
- To compare motility patterns between children with and without a history of fundoplication.
- To determine if fundoplication impacts antroduodenal motility or symptom resolution.
Main Methods:
- Antroduodenal manometry was performed on 55 children with upper gastrointestinal motor dysfunction symptoms.
- 28 of these children had previously undergone fundoplication.
- Motility data were compared between the fundoplication group and a control group of unoperated children.
Main Results:
- Abnormal antroduodenal motility was prevalent in both groups (25/28 fundoplication vs. 25/27 controls).
- Fundoplication did not alter the type or severity of motility abnormalities.
- Symptoms remained unchanged or worsened in all children who had fundoplication.
Conclusions:
- Fundoplication failed to alleviate severe functional gastrointestinal symptoms in this cohort.
- Preoperative antroduodenal manometry may be valuable in predicting surgical outcomes.
- Identifying physiological abnormalities preoperatively could guide treatment decisions and avoid ineffective surgeries.