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Updated: Jun 12, 2026

Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
Published on: December 10, 2016
Correlations between bed occupancy rates and Clostridium difficile infections: a time-series analysis
K Kaier1, D Luft, M Dettenkofer
1Department of Environmental Health Sciences, University Medical Center Freiburg, Germany. klaus.kaier@uniklinik-freiburg.de
Abstract:
A time-series analysis was performed to identify the impact of bed occupancy rates and length of hospital stay on the incidence of Clostridium difficile infections (CDI). Between January 2003 and July 2008, a mean incidence of 0·5 CDI cases/1000 patient days was recorded. Application of a multivariate model (R2=0·50) showed that bed occupancy rates on general wards (P<0·01) and length of stay in intensive care units (ICUs) (P<0·01) influenced the incidence of CDI. Overcrowding on general wards and long periods in ICUs were identified as being positively associated with the incidence of CDI.
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