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Related Concept Videos

Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Inhibitors Of Virion Release01:25

Inhibitors Of Virion Release

Viral replication and dissemination rely on efficient mechanisms for host cell entry, genome replication, assembly, and release. Influenza viruses, such as types A and B, are negative-sense single-stranded RNA viruses with a segmented genome, that depend on two critical surface glycoproteins to carry out these processes: hemagglutinin (HA) and neuraminidase (NA). HA initiates infection by binding to sialic acid residues on the surface of host epithelial cells, facilitating receptor-mediated...
Viruses with RNA Genomes01:29

Viruses with RNA Genomes

RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
Antiviral Nucleoside Inhibitors01:22

Antiviral Nucleoside Inhibitors

Antiviral Nucleoside InhibitorsAntiviral nucleoside inhibitors are structural analogs of natural nucleosides that interfere with viral DNA or RNA synthesis. These compounds selectively target viral polymerases due to their resemblance to host nucleosides, thereby disrupting viral genome replication.Mechanism of Acyclovir ActionAcyclovir is a guanosine analog with a three-carbon acyclic side chain. It selectively targets herpes simplex virus type 1 (HSV-1), herpes simplex virus type 2 (HSV-2),...
Human Virome01:26

Human Virome

The human body harbors a vast and diverse viral community known as the human virome. The virome includes bacteriophages that infect bacteria, and eukaryotic viruses that infect human cells. Transient dietary and environmental viruses also contribute to this dynamic ecosystem. Estimates suggest the human body may contain on the order of 10¹³ viral particles, though abundance varies widely by body site and detection method.Comprehensive characterization of the virome has become possible only with...

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Related Experiment Video

Updated: Jun 12, 2026

Preparation of Pseudo-Typed H5 Avian Influenza Viruses with Calcium Phosphate Transfection Method and Measurement of Antibody Neutralizing Activity
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Preparation of Pseudo-Typed H5 Avian Influenza Viruses with Calcium Phosphate Transfection Method and Measurement of Antibody Neutralizing Activity

Published on: November 22, 2021

Hantaviruses.

Mohammed A Mir1

  • 1Department of Microbiology, Molecular Genetics and Immunology, Kansas University Medical Center, Kansas City, 66103, USA. mmir@kumc.edu

Clinics in Laboratory Medicine
|June 2, 2010
PubMed
Summary
This summary is machine-generated.

Hantaviruses are a global health concern that are not well understood. This review covers hantavirus history, diagnostics, and potential treatments and prevention strategies.

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Highly Sensitive Assay for Measurement of Arenavirus-cell Attachment
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Last Updated: Jun 12, 2026

Preparation of Pseudo-Typed H5 Avian Influenza Viruses with Calcium Phosphate Transfection Method and Measurement of Antibody Neutralizing Activity
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Preparation of Pseudo-Typed H5 Avian Influenza Viruses with Calcium Phosphate Transfection Method and Measurement of Antibody Neutralizing Activity

Published on: November 22, 2021

Highly Sensitive Assay for Measurement of Arenavirus-cell Attachment
08:34

Highly Sensitive Assay for Measurement of Arenavirus-cell Attachment

Published on: March 2, 2016

Area of Science:

  • Virology
  • Infectious Diseases
  • Public Health

Background:

  • Hantaviruses are zoonotic viruses with a worldwide distribution.
  • Despite their global impact, hantaviruses remain poorly understood by the scientific community.
  • Understanding hantavirus epidemiology is crucial for public health.

Purpose of the Study:

  • To provide a comprehensive overview of the known history of hantaviruses.
  • To detail current diagnostic methods for hantavirus infections.
  • To explore potential treatment and prevention strategies for hantaviruses.

Main Methods:

  • Literature review of historical and scientific documents.
  • Analysis of diagnostic techniques for hantavirus detection.
  • Review of existing and proposed therapeutic and prophylactic measures.

Main Results:

  • The article traces the historical discovery and evolution of hantavirus research.
  • It outlines various diagnostic approaches, including serological and molecular methods.
  • Potential treatment avenues and preventive measures are discussed.

Conclusions:

  • Further research is needed to fully understand hantavirus pathogenesis and transmission.
  • Improved diagnostics and effective treatments are essential for managing hantavirus infections.
  • Public health strategies focusing on prevention are key to controlling hantavirus spread.