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Published on: May 11, 2015
Pulmonary hypertension in patients with chronic myeloproliferative disorders
1Pulmonary Divison, Carmel Medical Center, Faculty of Medicine, Technion, Institute of Technology, 7 Michal St., Haifa, Israel. adir-sh@zahav.net.il
Abstract:
Pulmonary hypertension (PH) is a severe haemodynamic disorder in which the pulmonary artery pressure is persistently elevated, leading to right-sided heart failure and death. Recently, chronic myeloproliferative diseases associated with pulmonary hypertension were included in the group 5 category, corresponding to PH for which the aetiology is unclear and/or multifactorial. In this review we will describe the distinct forms of PH in the context of the myeloproliferative diseases chronic thromboembolic pulmonary hypertension and pre-capillary PH mimicking pulmonary arterial hypertension. The epidemiology, mechanisms and treatment approaches will be discussed.
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