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Massive localized lymphedema: A soft tissue process that may present to dermatologists
Nadia S Wang1, Ruth F Walters, Simon J Warren
1Department of Dermatology, New York University School of Medicine, New York, 10016, USA. nadiaswang@hotmail.com
The American Journal of Dermatopathology
|June 2, 2010
Summary
Massive localized lymphedema (MLL) is a distinct condition in obese patients, characterized by specific skin changes. Early recognition and surgical options are crucial for managing this condition and its complications like cellulitis.
Area of Science:
- Dermatology
- Pathology
- Endocrinology
Background:
- Massive localized lymphedema (MLL) is a rare condition affecting morbidly obese individuals.
- It presents as a distinct clinical and histological entity.
Observation:
- Two obese patients with MLL in the lower abdomen and suprapubic region were studied.
- One patient had a history of hypothyroidism, a previously noted association.
Findings:
- Histological examination revealed characteristic features: expanded dermis with lymphangiectases, fibrotic septae, and focal fat necrosis.
- These findings can be mistaken for liposarcoma by inexperienced dermatopathologists.
Implications:
- MLL can lead to recurrent cellulitis, necessitating prompt diagnosis and management.
- Surgical intervention may be a viable treatment option for MLL.
- Dermatologists should be aware of MLL's distinct histopathologic features to avoid misdiagnosis.
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