Related Experiment Video
Updated: Jun 12, 2026

08:35
A Simple and Inexpensive Method for Determining Cold Sensitivity and Adaptation in Mice
Published on: March 17, 2015
Different types of cold adaptation in humans.
1Institute of Health Sciences, PO Box 5000, FI-90014 University of Oulu, Oulu, Finland. tiina.makinen@oulu.fi
Frontiers in Bioscience (Scholar Edition)
|June 3, 2010
Summary
Human adaptation to cold involves physiological and behavioral changes. These responses, including insulative and metabolic adjustments, vary based on exposure type and individual factors, with unclear long-term benefits.
Area of Science:
- Physiology
- Human Adaptation
- Thermoregulation
Background:
- Human adaptation to cold encompasses genetic, physiological, morphological, and behavioral responses.
- Studies investigate cold adaptation in diverse populations and conditions, yielding varied results.
- Key responses include insulative (circulatory, fat layer) and metabolic (thermogenesis) adjustments, which can be enhanced or blunted.
Purpose of the Study:
- To summarize recent research on thermoregulatory responses to repeated cold exposure (air or water).
- To discuss the determinants influencing cold adaptation.
- To explore the functional significance of physiological cold adaptation.
Main Methods:
- Review of existing research on human adaptation to cold.
- Analysis of studies involving indigenous populations, expeditions, sports, military training, and controlled exposures.
- Examination of factors modifying cold responses.
Main Results:
- Cold adaptation patterns depend on exposure type (air, water) and intensity (continuous, intermittent).
- Individual factors (age, sex, body composition, fitness, etc.) significantly modify cold adaptation responses.
- Habituation of thermal sensation precedes cardiovascular, metabolic, and endocrinological changes; adaptation diminishes upon cessation of cold stimulus.
Conclusions:
- The functional significance of physiological cold adaptation remains unclear.
- Some cold adaptation responses may be detrimental, increasing susceptibility to cold injuries.
- Understanding cold adaptation determinants and significance is crucial for optimizing human resilience to cold environments.
Related Concept Videos
Responses to Heat and Cold Stress
Every organism has an optimum temperature range within which healthy growth and physiological functioning can occur. At the ends of this range, there will be a minimum and maximum temperature that interrupt biological processes.
Natural Selection and Adaptation
Natural selection, a fundamental concept in evolutionary biology, is the mechanism by which evolution is driven, favoring organisms that are best adapted to their environments. This process enhances their chances of survival and reproduction. Adaptation, a key outcome of this process, involves genetic modifications that optimize an organism's functionality under specific environmental challenges, such as extreme cold or thinner air at high altitudes.
Beyond physical adaptations, psychological...
Beyond physical adaptations, psychological...
Requirements for Human Life
The Earth and its atmosphere have provided humans with air, water, and food, but these are not the only requirements for survival. Humans also require a specific range of temperature and pressure that the Earth and its atmosphere provides.
Oxygen
Atmospheric air is only about 20 percent oxygen, but that oxygen is a key component of the chemical reactions that keep the body alive, including the reactions that produce ATP. Brain cells are susceptible to a lack of oxygen because they require a...
Oxygen
Atmospheric air is only about 20 percent oxygen, but that oxygen is a key component of the chemical reactions that keep the body alive, including the reactions that produce ATP. Brain cells are susceptible to a lack of oxygen because they require a...
Decreased Body Temperature
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...
Factors Influencing Microbial Growth: Temperature
Microorganisms display remarkable adaptations, enabling them to thrive in diverse ecological niches across a wide range of temperatures. Temperature profoundly influences microbial growth by affecting enzymatic activity, membrane fluidity, and other cellular processes.Each microorganism operates within a specific temperature range defined by three cardinal points: minimum, optimum, and maximum. Below the minimum temperature, membranes lose fluidity, halting transport processes. Above the...
Thermosensation
Peripheral thermosensation is the perception of external temperature. A change in temperature (on the surface of the skin and other tissues) is detected by a family of temperature-sensitive ion channels called Transient Receptor Potential, or TRP, receptors. These receptors are located on free nerve endings. Those detecting cold temperatures are closer to the surface of the skin than the nerve endings detecting warmth. These thermoTRP channels, while temperature selective, have relatively...

