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Updated: Jun 12, 2026

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)

Published on: August 4, 2018

Scanning system design for large scan depth anterior segment optical coherence tomography.

Rahul Yadav¹, Kamran Ahmad, Geunyoung Yoon

¹The Institute of Optics, University of Rochester, Rochester New York 14627, USA. yadav@optics.rochester.edu

|June 3, 2010

Summary

This study introduces a novel optical coherence tomography scanning system to improve ocular imaging. The new system enhances signal-to-noise ratio (SNR) for better visualization of the cornea and lens surfaces.

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Area of Science:

Ophthalmic imaging
Biomedical optics
Optical coherence tomography

Background:

Telecentric scanning in ocular imaging causes reduced signal quality due to increased incidence angles on ocular surfaces.
This signal reduction is particularly problematic for regions farther from the optical axis, impacting diagnostic accuracy.

Purpose of the Study:

To develop and evaluate a novel optical coherence tomography (OCT) scanning system.
To achieve nearly normal incidences across ocular surfaces for improved signal acquisition.
To enhance the signal-to-noise ratio (SNR) in ocular OCT imaging.

Main Methods:

A new OCT scanning system was designed to maintain near-normal incidence angles.
The proposed system was compared against conventional telecentric scanning using a model eye.
Signal-to-noise ratio (SNR) was measured for anterior and posterior corneal and lens surfaces.

Main Results:

The proposed scanning system demonstrated significant SNR improvements across ocular surfaces.
SNR gains of 5dB (anterior lens) and 12dB (posterior lens) were observed.
Substantial SNR increases of 4dB (posterior cornea) and 0.7dB (anterior cornea) were also recorded.

Conclusions:

The proposed OCT scanning system effectively mitigates signal loss associated with telecentric scanning.
Achieving near-normal incidences significantly enhances SNR, leading to higher quality ocular images.
This advancement holds potential for improved diagnosis and monitoring of ocular conditions.