[Catecholaminergic polymorphic ventricular tachycardia in adult: a case report]

Area of Science:

• Cardiology
• Electrophysiology
• Genetics

Background:

• Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare genetic disorder affecting young individuals, causing life-threatening arrhythmias.
• Typically presenting in childhood or adolescence, CPVT is characterized by exercise- or stress-induced ventricular tachycardia, syncope, and sudden cardiac death.
• Standard management involves beta-blockers and, in refractory cases, implantable cardioverter-defibrillators (ICDs).

Observation:

• A 43-year-old male presented with exertional palpitations, leading to the diagnosis of CPVT.
• Holter ECG monitoring revealed supraventricular tachycardia and nocturnal sinoatrial block.
• The patient was managed with beta-blockade and an ICD implantation.

Findings:

• Adult-onset CPVT can manifest with attenuated symptoms, primarily exertional palpitations.
• Electrocardiographic findings may prominently feature supraventricular arrhythmias and sinus node dysfunction.
• The prognosis for adult CPVT appears more favorable compared to pediatric cases.

Implications:

• This case highlights the importance of considering CPVT in adults presenting with unexplained exertional palpitations.
• Sinus node dysfunction can influence treatment decisions, potentially necessitating ICD implantation alongside beta-blockade.
• Recognizing atypical presentations of CPVT is vital for timely diagnosis and improved patient outcomes.