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Updated: Jun 12, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
[Ear nose sarcoma. Report of 3 cases]
A Sethom1, K Akkari, A Hachicha
1Service d'oto-rhino-laryngologie et de chirurgie maxillo-faciale de l'Hôpital Militaire principal d'instruction de Tunis.
Background:
Head and neck sarcoma are very rare malignant tumors which can occur on any different ENT localization.
Aim:
The authors report tree different variety of ENT sarcoma diagnosed and treated at the oto-rhino-laryngological department of military hospital of Tunis. We intend to remind of clinical and histological particularities, therapeutic modalities and finally to evaluate the follow-up.
Methods:
From 2001 to 2007, three cases of head and neck sarcomas were diagnosed in ENT department of military hospital of Tunis.
Result:
the study concerned a women (22 years old) and two men 36 and 76 years old. It deals with an orbital rhabdomyosarcoma, a carcinosarcoma of submandibular gland and a maxillary chondrosarcoma. In each case, diagnosis was validated by the immunohistochemistry. All patients had surgical removal of their tumor. External irradiation or/and chemotherapy was also indicated for all cases.
Conclusion:
ENT sarcomas are aggressive neoplasm. Long-term survival is bad with high potentialities of local recurrence and distant metastases.
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