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Related Concept Videos

Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Male Sexual Response: Erection & Ejaculation01:17

Male Sexual Response: Erection & Ejaculation

Sexual stimulation can take various forms, such as physical touch and visual or auditory cues. When this happens, the parasympathetic reflex in the sacral portion of the spinal cord is activated. This reflex stimulates the release of nitric oxide (NO), which then dilates the arterioles in the penis, increasing blood flow to the erectile tissues - the corpora cavernosa and corpus spongiosum.
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
Menopause01:28

Menopause

Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors01:28

Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors

Phosphodiesterase 5 (PDE5) inhibitors are potent enzymes that function to hydrolyze cyclic nucleotides to their corresponding 5' monophosphates. Their unique biochemical properties have been applied in treating Pulmonary Arterial Hypertension (PAH).
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Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...

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Related Experiment Video

Updated: Jun 12, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Erectile dysfunction in aging male.

Francesco Romanelli1, Andrea Sansone, Andrea Lenzi

  • 1Department of Medical Pathophysiology, Sapienza University of Rome, Italy. francesco.romanelli@uniroma1.it

Acta Bio-Medica : Atenei Parmensis
|June 4, 2010
PubMed
Summary
This summary is machine-generated.

Erectile dysfunction (ED) is common in aging men and linked to vascular issues, metabolic syndrome, and medications. Treatment, including testosterone therapy and PDE-5 inhibitors, is safe and effective in older adults.

Related Experiment Videos

Last Updated: Jun 12, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
04:22

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Area of Science:

  • Gerontology
  • Sexual Medicine
  • Urology

Background:

  • Sexual health concerns are rising due to increased longevity.
  • Erectile dysfunction (ED) prevalence and severity increase with age.
  • ED is a symptom requiring diagnosis of underlying pathologies.

Purpose of the Study:

  • To explore the multifactorial nature of ED in aging men.
  • To highlight the role of vascular, metabolic, hormonal, and psychological factors in ED.
  • To discuss effective and safe treatment options for ED in the elderly.

Main Methods:

  • Review of age-related sexual health issues and ED.
  • Analysis of cardiovascular alterations, diabetes, smoking, and lifestyle factors impacting erectile function.
  • Examination of metabolic syndrome, psychological factors, and drug-induced ED.

Main Results:

  • Cardiovascular changes impair penile blood flow, contributing to ED.
  • Diabetes, smoking, and sedentary lifestyles are significant risk factors for ED.
  • Hypogonadism, metabolic syndrome, and certain medications can cause or exacerbate ED.

Conclusions:

  • ED in aging men is often multifactorial, involving vascular, metabolic, and hormonal aspects.
  • Testosterone replacement therapy, especially combined with PDE-5 inhibitors, is effective and safe in elderly men.
  • These treatments may also alleviate lower urinary tract symptoms in aging men.