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Published on: November 16, 2011
Hyperinsulinism assessment in a sample of prepubescent children
Stephanye Felicye Armecy Mieldazis1, Ligia Ajaime Azzalis, Virginia Berlanga Campos Junqueira
1Faculdade de Medicina do ABC (FMABC), SP, Brazil.
Objectives:
To determine the relationship between body mass index (BMI), homeostasis model assessment insulin resistance (HOMA-IR) and insulinemia.
Methods:
This was a prospective cross-sectional observational study of 132 prepubescent schoolchildren residents in the municipality of Santo André, Brazil. Children underwent anthropometric assessment, their glycemia and insulinemia were measured and their HOMA-IR index calculated.
Results:
Seventy-eight of the 132 children (59.1%) were girls and 54 were boys (40.9%), with a mean age of 8.7 years and mean BMI of 13.7 kg/m(2). A significant positive association was detected between HOMA-IR and BMI, insulin and BMI, weight and HOMA and between insulin and weight. It was also found that the higher the BMI, the greater the HOMA score.
Conclusions:
The results of this study allow for the conclusion that there is a strong association between hyperinsulinism and obesity. Measures should be taken to avoid weight gain during childhood and adolescence.
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