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Novel Percutaneous Approach for Deployment of 3D Printed Coronary Stenosis Implants in Swine Models of Ischemic Heart Disease
Published on: February 18, 2020
[Imaging of coronary stents using multislice computed tomography]
H Seifarth1, W Heindel, D Maintz
1Institut für Klinische Radiologie, Universitätsklinikum Münster, Albert-Schweitzer-Str. 33, 48149, Münster, Deutschland. seifarth@uni-muenster.de
Insights
Drug-eluting stents improve coronary artery stenting but increase thrombosis risk. Multislice computed tomography (MSCT) can visualize stents, but blooming artifacts hinder lumen delineation. Edge-enhancing kernels improve visualization at the cost of increased noise.
Area of Science:
- Cardiovascular Imaging
- Medical Device Technology
Background:
- Coronary artery stenting is a key revascularization method.
- Drug-eluting stents (DES) reduce restenosis but increase late stent thrombosis.
- Multislice computed tomography (MSCT) visualizes coronary stents, yet blooming artifacts impede lumen assessment.
Purpose of the Study:
- To investigate factors affecting stent lumen visualization in MSCT.
- To evaluate the impact of convolution kernels on blooming artifacts.
- To identify optimal conditions for MSCT stent imaging.
Main Methods:
- Analysis of blooming artifact severity based on stent strut thickness, design, and material.
- Comparison of different convolution kernels (soft, medium, edge-enhancing) for image reconstruction.
- Assessment of stent lumen visualization in relation to stent diameter and location.
Main Results:
- Blooming artifacts significantly hamper stent lumen delineation in MSCT.
- Edge-enhancing kernels improve lumen visualization compared to soft/medium kernels, but increase image noise.
- Optimal visualization is typically achieved for stents >3 mm in diameter, located proximally, and perpendicular to the scanner's z-axis.
Conclusions:
- MSCT stent imaging remains challenging due to blooming artifacts.
- Convolution kernel selection is critical for enhancing stent lumen visualization.
- Stent characteristics and positioning influence imaging quality, impacting diagnostic accuracy.
Abstract:
Coronary artery stenting has become the most important form of coronary revascularization. With the introduction of drug-eluting stents (DES) the rate of restenosis has declined but due to the delayed formation of intimal tissue the incidence of late (>30 days after stent placement) and very late thrombosis of the stents is higher for DES. Visualization of the stent lumen is possible with multislice computed tomography (MSCT) but blooming artifacts hamper the delineation of the stent lumen. The severity of these artifacts and thus the width of the visible stent lumen depends on several factors, such as the thickness of the stent struts, the design of the stent and the underlying material itself. The most important factor influencing the extent of blooming artifacts is the convolution kernel selected for image reconstruction. Dedicated, edge-enhancing kernels offer superior lumen visualization compared to the soft or medium kernels used for coronary artery imaging. The trade-off using edge-enhancing kernels is an increase in image noise.Despite all efforts undertaken to enhance stent lumen visualization, stent imaging is still a challenge in MSCT. In the majority of stents currently used, sufficient lumen visualization is only possible in stents with a diameter larger than 3 mm. A position of the stent in the proximal segments of the coronary artery tree facilitates delineation of the stent lumen not only because of the relatively little motion but also because of the lesser extent of blooming artifacts obscuring the stent lumen if the stent is oriented perpendicular to the z-axis of the scanner.
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