Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

Kidney Transplant II: Surgical Procedure

Kidney Transplant II: Surgical Procedure

Preoperative ManagementThe primary goals of preoperative management in kidney transplantation are to optimize the patient’s metabolic state and prepare them for surgery through diet adjustments, necessary dialysis, and tailored medical treatment. This phase also involves comprehensive infection screening and patient education about the surgical procedure and postoperative care to improve outcomes and adherence.Medical ManagementA comprehensive evaluation is required for both the living donor...

Kidney Transplant III: Nursing Management

Kidney Transplant III: Nursing Management

Postoperative Nursing Management for Kidney Transplant PatientsPostoperative nursing management care includes monitoring the surgical site, encouraging early movement, and promoting lung health through breathing exercises. Nurses also administer prescribed medications like H2-blockers, such as famotidine, or proton pump inhibitors, like omeprazole, to help prevent gastrointestinal ulcers and bleeding. Fungal infections in the mouth and bladder can result from immunosuppressive and antibiotic...

Tissue Transplantation

Tissue Transplantation

Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
The Biology of Tissue Transplantation
The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...

Kidney Structure

Kidney Structure

The kidneys are two large bean-shaped organs located in the upper abdomen. They filter the blood several times a day to remove toxins and rebalance water and electrolytes of the circulatory system via the renal veins. The kidneys receive blood directly from the heart via the renal arteries. These arteries enter the kidney at the hilum, the concave surface of the bean, where they branch and divide into smaller vessels and capillaries.

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease I: Introduction

Chronic Kidney Disease (CKD) arises when the kidneys progressively lose their ability to function, ultimately leading to end-stage renal disease. At this advanced stage, the kidneys can no longer filter waste or maintain essential body functions, requiring renal replacement therapy (RRT) through dialysis or a kidney transplant for survival.Early-stage chronic kidney disease and detection challengesIn CKD's early stages, symptoms often remain absent because healthy nephrons compensate for...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Sequential Donation: Evaluating Safety and Quality of Life of Living Donors.

Clinical transplantation·2026

Same author

Association Between Time Spent With Low Posttransplant Glomerular Filtration Rate and Access to Relisting and Retransplantation.

Kidney medicine·2026

Same author

Cosmic Kidney Disease: Countermeasures to Attenuate Kidney Damage in Space.

Clinical journal of the American Society of Nephrology : CJASN·2026

Same author

National access to renal transplantation and post-transplant survival among patients with diabetes: deceased and living donor outcomes.

BMJ open diabetes research & care·2026

Same author

Regarding "The Efficacy and Safety of Technology-Guided Dry Weight Adjustment Among Dialysis Patients: A Meta-Analysis of Randomized Controlled Trials" by Wathanavasin et al.

Kidney medicine·2026

Same author

Cytomegalovirus (CMV) Serostatus Reassessment in CMV Seronegative Kidney Transplant Candidates.

Transplant infectious disease : an official journal of the Transplantation Society·2025

Search research articles

Related Experiment Video

Updated: Jun 12, 2026

Using a Chemical Biopsy for Graft Quality Assessment

Using a Chemical Biopsy for Graft Quality Assessment

Published on: June 17, 2020

Death with functioning kidney transplant: an obituarial analysis.

Puneet Sood¹, Yong R Zhu, Eric P Cohen

¹Division of Nephrology, University of California, 521 Parnassus Avenue, Clinical Sciences, Room C443, San Francisco, CA 94143-0532, USA. puneet.sood@ucsf.edu

International Urology and Nephrology

|June 4, 2010

Summary

Improved medical care has increased the time to death with a functioning kidney graft (DWFG) to 10 years. This trend highlights advancements in transplant recipient care and outcomes.

More Related Videos

Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol

Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol

Published on: February 21, 2016

Related Experiment Videos

Last Updated: Jun 12, 2026

Using a Chemical Biopsy for Graft Quality Assessment

Using a Chemical Biopsy for Graft Quality Assessment

Published on: June 17, 2020

Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol

Heterotopic Renal Autotransplantation in a Porcine Model: A Step-by-Step Protocol

Published on: February 21, 2016

Area of Science:

Nephrology
Transplantation Medicine
Public Health

Background:

Death with a functioning kidney graft (DWFG) is a significant cause of graft loss, impacting up to 40% of renal transplant cases.
Analyzing DWFG provides critical insights into the quality of medical care for kidney transplant recipients.

Purpose of the Study:

To evaluate whether advancements in medical care have led to improved outcomes in kidney transplantation.
To assess trends in the time to death with a functioning kidney graft (DWFG) as an indicator of transplant care quality.

Main Methods:

Utilized single-center data from 3,157 kidney-only transplants performed between 1969 and 2005.
Analyzed 714 cases of death with a functioning kidney graft (DWFG), examining causes across three distinct time epochs.
Employed a serial collection of yearly obituaries for data analysis.

Main Results:

The mean time to death with a functioning kidney graft (DWFG) has significantly increased to 10 years.
This improvement was observed despite a 20-year increase in the average age of kidney transplant recipients during the study period.

Conclusions:

Enhanced pre-transplant evaluations have likely contributed to better patient selection and outcomes.
Improvements in managing hypertension, hyperlipidemia, and acute myocardial infarction have positively impacted graft and patient survival.
Superior immunosuppressive protocols and enhanced prophylaxis/treatment of infectious diseases are key factors in the observed trend of increased DWFG survival.