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[PAH exposure in asphalt workers].

Siria Garattini¹, Michela Sarnico, Alessandra Benvenuti

¹Servizio Prevenzione e Sicurezza Ambienti di Lavoro, ASL Brescia. siria.garattini@aslbrescia.it

La Medicina Del Lavoro

|June 5, 2010

Summary

This summary is machine-generated.

Asphalt workers show higher polycyclic aromatic hydrocarbon (PAH) exposure than the general population, indicating personal protective equipment is insufficient. Biomonitoring of urinary 1-hydroxypyrene (1-OHP) is crucial for assessing PAH exposure and risk in these workers.

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Area of Science:

Occupational Health
Environmental Science
Toxicology

Background:

Bitumen fumes in asphalt work have been evaluated for carcinogenicity since the 1960s.
International Agency for Research on Cancer (IARC) classifies air-refined bitumens as possible human carcinogens.
Urinary 1-hydroxypyrene (1-OHP) is a key biomarker for polycyclic aromatic hydrocarbon (PAH) exposure in asphalt workers.

Purpose of the Study:

To assess asphalt workers' exposure levels through 1-OHP urinary excretion.
To compare exposure data between asphalt workers and non-occupationally exposed individuals.

Main Methods:

Investigated three groups of asphalt workers (n=100 in summer 2007, n=29 in winter 2007, n=148 in summer 2008).
Measured 1-OHP urinary concentrations as a biomarker of PAH exposure.
Utilized Kruskal-Wallis test to compare 1-OHP concentrations across groups.

Main Results:

Median 1-OHP urinary concentrations were 0.65, 0.17, and 0.53 microg/g creatinine across the sampling periods.
A statistically significant difference (p < 0.001) in 1-OHP values was observed between the three study groups.

Conclusions:

Asphalt workers exhibit higher PAH exposure than the general and urban populations.
Current personal protective equipment (PPE) is inadequate for controlling PAH exposure in these workers.
Biomonitoring of 1-OHP is essential for evaluating PAH exposure, risk assessment, and enforcing regulations for carcinogen-exposed workers.