Related Experiment Video
Updated: Jun 12, 2026

Deep Neuromuscular Blockade Leads to a Larger Intraabdominal Volume During Laparoscopy
Published on: June 25, 2013
Postoperative pain after laparoscopic and vaginal hysterectomy for benign gynecologic disease: a randomized trial
Fabio Ghezzi1, Stefano Uccella, Antonella Cromi
1Department of Obstetrics and Gynecology, Del Ponte Hospital, University of Insubria, Varese, Italy. fabio.ghezzi@uninsubria.it
Objective:
To compare postoperative pain after laparoscopic and vaginal hysterectomy for benign disease.
Study Design:
A prospective randomized trial was designed to compare laparoscopic hysterectomy and vaginal hysterectomy in patients with uterine volume
Results:
A total of 82 patients were enrolled. Patients who underwent vaginal hysterectomy complained of higher postoperative pain at each VAS evaluation (VAS-1 hour, P < .0001; VAS-3 hour, P < .0001; VAS-8 hour, P < .0001; VAS-24 hour, P = .0003) with a higher need for rescue analgesia (P < .0001) and a longer hospitalization (P = .001). The other perioperative characteristics were comparable between the 2 groups.
Conclusion:
Laparoscopic hysterectomy provides an advantage over vaginal hysterectomy in terms of postoperative pain, need for rescue analgesia and hospital stay, with similar perioperative outcomes.
