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Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Related Experiment Video

Updated: Jun 12, 2026

Imaging Neurons within Thick Brain Sections Using the Golgi-Cox Method

Imaging Neurons within Thick Brain Sections Using the Golgi-Cox Method

Published on: April 18, 2017

Neuroimaging in Cockayne syndrome.

M Koob¹, V Laugel, M Durand

¹Departments of Radiology II, Strasbourg Hautepierre University Hospital, 1 Avenue Molière, Strasbourg Cedex, France. meriam.koob@chru-strasbourg.fr

AJNR. American Journal of Neuroradiology

|June 5, 2010

Summary

This summary is machine-generated.

Cerebral sclerosis (CS) is a genetic disorder causing neurologic issues. Neuroimaging reveals hypomyelination, calcifications in the putamen, and brain atrophy, aiding diagnosis.

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Related Experiment Videos

Last Updated: Jun 12, 2026

Imaging Neurons within Thick Brain Sections Using the Golgi-Cox Method

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Published on: April 18, 2017

Chronic Imaging of Mouse Visual Cortex Using a Thinned-skull Preparation

Chronic Imaging of Mouse Visual Cortex Using a Thinned-skull Preparation

Published on: October 25, 2010

A Micro-CT-based Method for Characterizing Lesions and Locating Electrodes in Small Animal Brains

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Published on: November 8, 2018

Area of Science:

Neurology
Radiology
Genetics

Background:

Cerebral sclerosis (CS) is an autosomal recessive multisystem disorder.
Key features include neurologic and sensory impairment, cachectic dwarfism, and photosensitivity.

Purpose of the Study:

To describe the neuroimaging features of various clinical subtypes of CS.
To correlate imaging findings with genetic and biochemical data.

Main Methods:

Utilized MR imaging, ¹H-MR spectroscopy, and CT scans.
Analyzed a cohort of genetically and biochemically confirmed CS cases.

Main Results:

Common findings include hypomyelination, calcifications (primarily in the putamen), and progressive brain atrophy.
Early-onset CS showed more severe hypomyelination and cortical calcifications.
MR spectroscopy detected lactate and decreased Cho and NAA values.

Conclusions:

Combined neuroradiologic findings are crucial for diagnosing CS.
These findings help differentiate CS from other childhood leukoencephalopathies and cerebral calcification disorders.