Related Experiment Video
Updated: Jun 12, 2026
08:51
Murine Appendectomy Model of Chronic Colitis Associated Colorectal Cancer by Precise Localization of Caecal Patch
Published on: August 24, 2019
Endocrine tumors of the appendix: a pathologic review
Lydia Deschamps1, Anne Couvelard
1Department of Pathology, Centre Hospitalier Universitaire La Meynard, Fort-de-France, France.
Archives of Pathology & Laboratory Medicine
|June 8, 2010
Summary
Appendiceal endocrine tumors, including classic types and goblet cell carcinoids, require specific pathology analysis. Classifications guide prognosis and management, with goblet cell carcinoids often needing hemicolectomy.
Area of Science:
- Gastroenterology
- Surgical Pathology
- Oncology
Background:
- Appendiceal endocrine tumors are the most common appendix neoplasms, though rare overall.
- Accurate pathologic analysis is crucial for effective patient management.
Purpose of the Study:
- To present current data on appendiceal endocrine tumor pathology.
- To detail classifications and patient management guidelines.
Main Methods:
- Literature review of recent studies.
- Inclusion of TNM classifications.
- Analysis of patient management guidelines.
Main Results:
- Appendiceal endocrine tumors are categorized into classic endocrine tumors and goblet cell carcinoids.
- WHO and TNM classifications aid in prognosis assessment.
- Tumor size, proliferation, and infiltration impact malignancy risk.
Conclusions:
- Classic appendiceal endocrine tumors generally have a favorable prognosis.
- Management strategies, including complementary surgery, are discussed, especially for tumors 1-2 cm.
- Goblet cell carcinoids typically warrant a right hemicolectomy post-appendectomy.
Related Concept Videos
01:19Appendicitis
Appendicitis is an acute inflammatory condition of the vermiform appendix, most commonly caused by obstruction of its lumen. The appendix is a narrow, blind-ended pouch that extends from the cecum, making it particularly prone to obstruction. Causes include fecaliths, lymphoid hyperplasia (often after viral infections), parasites, tumors, or foreign bodies. This obstruction initiates a cascade of pathological changes.Luminal Obstruction and Early InflammationAfter obstruction, normal mucosal...
01:22Appendicitis-I: Introduction
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
01:29Appendicitis-II: Diagnostic Studies and Management
Diagnosing and managing appendicitis requires a structured and comprehensive approach that spans from initial assessment to postoperative care. Here is an overview of the process:
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...
Diagnosing Appendicitis
It requires a multifaceted approach, starting with a detailed physical examination to pinpoint the location and nature of the pain and identify any associated symptoms. Laboratory tests play a crucial role. A complete Blood Count (CBC) typically reveals leukocytosis (an increased number of...