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Related Concept Videos

Allergic Reactions: Anaphylaxis01:30

Allergic Reactions: Anaphylaxis

Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin, heparin),...
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Cross-reactivity00:42

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Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
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Allergic Drug Reactions

Allergic reactions related to drugs are hypersensitivity responses driven by the immune system and bear no connection to the drug's therapeutic action. While drugs in isolation do not trigger an immune response, they can interact with endogenous proteins to form antigens. These antigens stimulate lymphocytes to produce antibodies. IgE-type antibodies attach themselves to mast cells. Upon subsequent exposure to the same stimulus, the antigen-antibody interaction is initiated, unleashing numerous...
Asthma: Pathogenesis and Management01:20

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.

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Related Experiment Video

Updated: Jun 12, 2026

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

Peanut allergy: an overview.

Nasser Al-Ahmed1, Shirina Alsowaidi, Peter Vadas

  • 1Division of Allergy and Clinical Immunology, St, Michael's Hospital, University of Toronto, Toronto, ON.

Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology
|June 8, 2010
PubMed
Summary
This summary is machine-generated.

Peanut allergies are rising globally, often starting in early childhood. While most cases are lifelong, some children may outgrow this severe food allergy.

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Last Updated: Jun 12, 2026

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07:22

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Non-destructive SPE-UPLC-based Quantification of Aflatoxins and Stilbenoid Phytoalexins in Single Peanut (Arachis spp.) Seeds
10:24

Non-destructive SPE-UPLC-based Quantification of Aflatoxins and Stilbenoid Phytoalexins in Single Peanut (Arachis spp.) Seeds

Published on: April 19, 2024

Area of Science:

  • Allergy and Immunology
  • Pediatrics
  • Epidemiology

Background:

  • Increasing global prevalence of peanut allergies, particularly in industrialized nations.
  • Typical onset in early childhood with a trend toward earlier presentation.
  • Peanut allergy is often lifelong, though a subset of children may outgrow it.

Purpose of the Study:

  • To review the current understanding of peanut allergy.
  • To discuss risk factors for severe reactions and potential causes for rising prevalence.
  • To outline investigation, treatment, and cross-reactivity patterns.

Main Methods:

  • Literature review of peanut allergy research.
  • Analysis of epidemiological trends and clinical manifestations.
  • Discussion of immunological and environmental factors.

Main Results:

  • Peanut allergy onset is trending earlier in childhood.
  • 15-22% of affected children may outgrow their allergy before adolescence.
  • Severe, life-threatening anaphylactic reactions can occur even without identified risk factors.

Conclusions:

  • Peanut allergy represents a significant and growing public health concern.
  • Understanding risk factors, cross-reactivity, and treatment is crucial.
  • Further research into the causes of rising prevalence is warranted.