Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Blood Studies for Cardiovascular System III: Serum Lipid Profile01:25

Blood Studies for Cardiovascular System III: Serum Lipid Profile

Understanding serum lipids is crucial for maintaining cardiovascular health and preventing heart disease and stroke.
Serum lipids are fats and fatty substances in the blood and are crucial for various bodily functions, including energy storage, cellular structure, and hormone production. Serum lipids consist of cholesterol, triglycerides, and phospholipids.
Cholesterol is a soft, fat-like substance found in all body cells. It is crucial for producing hormones, vitamin D, and substances that aid...
Lipid-derived Compounds in the Human Body01:31

Lipid-derived Compounds in the Human Body

Fats and lipids are crucial components in the human body. Some lipid-derived compounds, such as fat-soluble vitamins, eicosanoids, lipoproteins, and glycolipids, also play unique roles to support various  biological processes .
Fat-soluble Vitamins
Fat-soluble vitamins, including vitamins A, D, E, and K, are required in minimal quantities, but their deficiencies can lead to severely abnormal physiological conditions. For example, vitamin A deficiency can cause night blindness, dry skin, delayed...
Lipid Absorption01:24

Lipid Absorption

Dietary triglycerides from chyme in the duodenum are mixed with bile salts produced by the liver to emulsify fats. As a result, large droplets are broken down into smaller ones, increasing the surface area for enzymatic action. Once emulsified, pancreatic lipases hydrolyze the triglycerides into free fatty acids and monoglycerides.
These breakdown products bind with bile salts and lecithin to form micelles, which quickly pass between microvilli to come in close contact with the apical...
Overview of Lipid Metabolism01:24

Overview of Lipid Metabolism

Lipid metabolism is a crucial process in the human body that involves the synthesis and degradation of lipids. This process is essential for energy production, cell membrane formation, and hormone production, among other functions.
Lipolysis: The Breakdown of Lipids:
Lipolysis is the process of breaking down lipids, particularly triglycerides, into glycerol and fatty acids. This process typically occurs in the adipose tissue and is triggered by various hormones, including glucagon and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Allergic but not autoimmune comorbidities in children with PFAPA: A nationwide matched case-control cohort study.

Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology·2026
Same author

IgE-Mediated Food Allergy in Patients with Celiac Disease.

Digestive diseases (Basel, Switzerland)·2026
Same author

The role of primary care in response to the global liver disease syndemic: a Lancet Gastroenterology & Hepatology Commission.

The lancet. Gastroenterology & hepatology·2026
Same author

Long-term rheumatologic comorbidities in familial Mediterranean fever.

Seminars in arthritis and rheumatism·2026
Same author

What is the prevalence of depression and anxiety in externally and internally displaced Ukrainian refugees? A European mixed-methods study.

BMC public health·2026
Same author

Fibromyalgia and Risk of Alzheimer's DiseaseRelated Dementia: A Nationwide Bidirectional Case-Control Study.

Geriatrics (Basel, Switzerland)·2026

Related Experiment Video

Updated: Jun 12, 2026

The Use of Gas Chromatography to Analyze Compositional Changes of Fatty Acids in Rat Liver Tissue during Pregnancy
11:08

The Use of Gas Chromatography to Analyze Compositional Changes of Fatty Acids in Rat Liver Tissue during Pregnancy

Published on: March 13, 2014

Lipid profile in consecutive pregnancies.

David Mankuta1, Matan Elami-Suzin, Asher Elhayani

  • 1Hadassah University Hospital Jerusalem Israel. mankutad@gmail.com

Lipids in Health and Disease
|June 8, 2010
PubMed
Summary

Pregnancy alters lipid profiles, increasing total cholesterol, LDL, and VLDL. Consecutive pregnancies cumulatively lower HDL cholesterol, potentially impacting long-term cardiovascular health in women.

Area of Science:

  • Reproductive Medicine
  • Cardiovascular Health
  • Biochemistry

Background:

  • Pregnancy significantly impacts maternal physiology, including metabolic and lipid profiles.
  • Understanding these changes is crucial for monitoring maternal health and long-term cardiovascular risk.

Purpose of the Study:

  • To characterize the lipid profile changes in women before, during, and after pregnancy.
  • To evaluate the cumulative impact of multiple pregnancies on plasma lipid levels.

Main Methods:

  • Analysis of lipid profiles (total cholesterol, LDL-C, HDL-C, VLDL-C, triglycerides) in 1752 women aged 20-45.
  • Measurements taken during non-pregnant states, three trimesters, and postpartum periods across up to three pregnancies.

Main Results:

More Related Videos

Stable Isotope In-Vivo Labeling for Mass-Spectrometry Identification of Paternal Metabolites Transferred from Sperm to Oocyte During Fertilization
05:55

Stable Isotope In-Vivo Labeling for Mass-Spectrometry Identification of Paternal Metabolites Transferred from Sperm to Oocyte During Fertilization

Published on: June 17, 2025

Isolation of Cellular Lipid Droplets: Two Purification Techniques Starting from Yeast Cells and Human Placentas
09:41

Isolation of Cellular Lipid Droplets: Two Purification Techniques Starting from Yeast Cells and Human Placentas

Published on: April 1, 2014

Related Experiment Videos

Last Updated: Jun 12, 2026

The Use of Gas Chromatography to Analyze Compositional Changes of Fatty Acids in Rat Liver Tissue during Pregnancy
11:08

The Use of Gas Chromatography to Analyze Compositional Changes of Fatty Acids in Rat Liver Tissue during Pregnancy

Published on: March 13, 2014

Stable Isotope In-Vivo Labeling for Mass-Spectrometry Identification of Paternal Metabolites Transferred from Sperm to Oocyte During Fertilization
05:55

Stable Isotope In-Vivo Labeling for Mass-Spectrometry Identification of Paternal Metabolites Transferred from Sperm to Oocyte During Fertilization

Published on: June 17, 2025

Isolation of Cellular Lipid Droplets: Two Purification Techniques Starting from Yeast Cells and Human Placentas
09:41

Isolation of Cellular Lipid Droplets: Two Purification Techniques Starting from Yeast Cells and Human Placentas

Published on: April 1, 2014

  • Total cholesterol, LDL-C, and triglycerides increased during pregnancy, returning to baseline postpartum.
  • HDL-C levels showed a transient increase in the second trimester but decreased overall with subsequent pregnancies.
  • Lower average HDL-C levels were observed in the second and third pregnancies compared to the first.

Conclusions:

  • Pregnancy induces significant, generally reversible, changes in lipid profiles.
  • Consecutive pregnancies have a cumulative negative effect on HDL-C levels.
  • The observed decline in HDL-C with repeated pregnancies may pose risks to future cardiovascular health.