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Related Concept Videos

Healing II: Complications01:24

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...
Reticular Dermis01:15

Reticular Dermis

The papillary and reticular dermis are the two layers of the dermis. They are made of connective tissue with fibers of collagen extending from one to the other, making the border between the two somewhat indistinct. The dermal papillae extending into the epidermis belong to the papillary layer, whereas the dense collagen fiber bundles below belong to the reticular layer.
Reticular Layer
Underlying the papillary layer is the much thicker reticular layer, composed of dense, irregular connective...
Clinical Applications of Epidermal Stem Cells01:19

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

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Related Experiment Video

Updated: Jun 12, 2026

The Combination of Mechanically Isolated Stromal Vascular Fraction and Fibrin Hydrogel: A Processing Protocol
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The Combination of Mechanically Isolated Stromal Vascular Fraction and Fibrin Hydrogel: A Processing Protocol

Published on: November 17, 2023

[Dermal fillers: types, indications, and complications].

I Sánchez-Carpintero1, D Candelas, R Ruiz-Rodríguez

  • 1Clínica Rúber, Madrid, España. ignacio@ricardoruiz.es <ignacio@ricardoruiz.es>

Actas Dermo-Sifiliograficas
|June 8, 2010
PubMed
Summary

Dermal fillers, including hyaluronic acid, are widely used for cosmetic and medical reasons. This review details filler types, techniques, indications, and complications for safe and effective use.

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Last Updated: Jun 12, 2026

The Combination of Mechanically Isolated Stromal Vascular Fraction and Fibrin Hydrogel: A Processing Protocol
05:30

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Published on: November 17, 2023

Assessment of Viability of Human Fat Injection into Nude Mice with Micro-Computed Tomography
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Assessment of Viability of Human Fat Injection into Nude Mice with Micro-Computed Tomography

Published on: January 7, 2015

Area of Science:

  • Dermatology and Aesthetic Medicine

Context:

  • Dermal fillers are extensively utilized in clinical practice for cosmetic and medical applications.
  • Classified by duration (temporary, semipermanent, permanent) and composition (collagen, hyaluronic acid, PLLA, CaHA, etc.).

Purpose:

  • To provide a comprehensive overview of dermal filler techniques and clinical indications.
  • To review the properties, mechanisms, and applications of various temporary, semipermanent, and permanent dermal fillers.
  • To discuss common complications and their management.

Summary:

  • Hyaluronic acid fillers are frequently chosen for cosmetic procedures due to ease of use, efficacy, and safety.
  • The review covers material science, application methods, and specific indications for different filler categories.
  • Management of adverse events associated with dermal fillers is also addressed.

Impact:

  • Enhances understanding of dermal filler science and clinical application.
  • Aids practitioners in selecting appropriate fillers and techniques for optimal patient outcomes.
  • Contributes to the safe and effective use of cosmetic and medical injectables.