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Related Concept Videos

Aging01:26

Aging

Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
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Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
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Alzheimer disease involves structural changes in the brain that begin long before symptoms appear. The most distinctive features are extracellular neuritic plaques and intracellular neurofibrillary tangles.Neuritic plaques form in the cerebral cortex and around blood vessels. These plaques contain a dense core of beta-amyloid (Aβ)—a toxic protein fragment that clumps outside neurons. The core is surrounded by damaged neuronal extensions, as well as reactive astrocytes and microglia. Abnormal...
Neuroplasticity01:01

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Related Experiment Video

Updated: Jun 12, 2026

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
10:13

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

[Cognitive reserve and neuronal changes associated with aging].

Sylvia Villeneuve1, Sylvie Belleville

  • 1Centre de recherche, Institut Universitaire de gériatrie de Montréal, Département de psychologie, Université de Montréal, Canada.

Psychologie & Neuropsychiatrie Du Vieillissement
|June 8, 2010
PubMed
Summary
This summary is machine-generated.

Cognitive reserve protects against cognitive decline in aging brain disorders. Higher cognitive reserve allows individuals to withstand more brain lesions before dementia symptoms appear.

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Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
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Related Experiment Videos

Last Updated: Jun 12, 2026

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach
10:13

Assessment of Age-related Changes in Cognitive Functions Using EmoCogMeter, a Novel Tablet-computer Based Approach

Published on: February 14, 2014

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology
14:57

Preparation of Acute Hippocampal Slices from Rats and Transgenic Mice for the Study of Synaptic Alterations during Aging and Amyloid Pathology

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06:58

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing

Published on: January 24, 2020

Area of Science:

  • Neuroscience
  • Cognitive Aging
  • Neurology

Context:

  • Age-related brain disorders often show a disconnect between brain lesion severity and cognitive deficits.
  • The cognitive reserve hypothesis offers an explanation for this discrepancy.

Purpose:

  • To review the concept of cognitive reserve.
  • To explore its underlying neuronal mechanisms and influencing factors.
  • To present key studies investigating cognitive reserve in clinical populations.

Summary:

  • Cognitive reserve acts as a buffer, reducing the impact of cerebral lesions on cognition.
  • Individuals with greater cognitive reserve can tolerate more neuropathology before dementia onset.
  • This review details factors that enhance or diminish cognitive reserve.

Impact:

  • Provides a novel perspective on cognitive aging, both normal and pathological.
  • Highlights the importance of cognitive reserve in understanding dementia.
  • Informs potential strategies for enhancing brain resilience.