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Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots
12:17

Full-root Aortic Valve Replacement by Stentless Aortic Xenografts in Patients with Small Aortic Roots

Published on: May 21, 2017

[The impact of the "patient - prosthesis mismatch" in patients with aortic valve replacement.]

Ricardo Ferreira1, A Nobre, J Gallego

  • 1Serviço de Cirurgia Cardiotorácica do Hospital de Santa Maria,CHLN, Lisboa.

Revista Portuguesa De Cirurgia Cardio-Toracica E Vascular : Orgao Oficial Da Sociedade Portuguesa De Cirurgia Cardio-Toracica E Vascular
|June 8, 2010
PubMed
Abstract

Insights

Patient-Prosthesis Mismatch (PPM) after aortic valve replacement is linked to higher short-term mortality but not long-term outcomes. This study found PPM impacts surgical times but not 2-year mortality or heart function.

Area of Science:

  • Cardiovascular Surgery
  • Prosthetic Valve Research
  • Clinical Outcomes Analysis

Context:

  • Patient-Prosthesis Mismatch (PPM) occurs when an implanted aortic prosthesis is too small for a patient's body surface area.
  • A PPM definition is an indexed orifice area <0.8-0.9 cm²/m².
  • The clinical significance of PPM remains a subject of debate.

Purpose:

  • To assess the short-term and 2-year impact of Patient-Prosthesis Mismatch (PPM) in patients undergoing aortic valve replacement.
  • To compare outcomes between patients with and without PPM.

Summary:

  • A retrospective study of 343 patients undergoing aortic valve replacement found PPM in 31.7% of cases.
  • PPM was associated with advanced age, biological prosthesis use, and smaller valve sizes.
  • Short-term mortality was significantly higher in patients with PPM (p<0.001).

Impact:

  • PPM correlated with increased aortic cross-clamping and extracorporeal circulation times.
  • No significant differences in 2-year mortality or NYHA class were observed between groups.
  • These findings suggest PPM's primary impact is on short-term surgical recovery rather than long-term survival or functional status.

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