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Fungal peritonitis in peritoneal dialysis: an analysis of 21 cases

Aydin Unal1, Ismail Kocyigit, Murat Hayri Sipahioglu

  • 1Department of Nephrology, Erciyes University Medical School, Kayseri, Turkey. aydinunal2003@gmail.com

International Urology and Nephrology
|June 8, 2010
PubMed
Abstract

Insights

Fungal peritonitis in peritoneal dialysis (PD) patients is serious. Successful management requires antifungal therapy and PD catheter removal, with Candida albicans being the most common cause.

Area of Science:

  • Nephrology
  • Infectious Diseases
  • Medical Mycology

Background:

  • Fungal peritonitis is a rare but severe complication in patients undergoing peritoneal dialysis (PD).
  • Understanding predisposing factors, clinical features, and causative agents is crucial for effective management.

Purpose of the Study:

  • To analyze predisposing factors, clinical aspects, and treatment outcomes of fungal peritonitis in PD patients.
  • To identify the most common etiological agents responsible for fungal peritonitis in this population.

Main Methods:

  • Retrospective analysis of PD patients from January 1995 to December 2009.
  • Inclusion of 21 patients diagnosed with fungal peritonitis.

Main Results:

  • Candida species, particularly Candida albicans (14/16), were the most frequent pathogens.
  • Peritoneal dialysis catheter removal was performed in all patients, with a significant decrease in removal time after 2005.
  • 19 patients were transferred to hemodialysis, and 2 patients died during the peritonitis episode.

Conclusions:

  • Candida albicans is the predominant pathogen causing fungal peritonitis in PD patients.
  • Successful management necessitates both antifungal therapy and peritoneal dialysis catheter removal.

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