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Pseudomembranous colitis: CT evaluation of 26 cases
E K Fishman1, M Kavuru, B Jones
1Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, MD.
Radiology
|July 1, 1991
Summary
Computed tomographic (CT) scans can help diagnose pseudomembranous colitis (PMC), an antibiotic-associated condition. While not definitive, CT findings like thickened bowel walls suggest PMC in patients with relevant symptoms.
Area of Science:
- Gastroenterology
- Radiology
- Infectious Diseases
Background:
- Pseudomembranous colitis (PMC) is an infectious colitis often linked to antibiotic use.
- Accurate and timely diagnosis is crucial for effective patient management.
Purpose of the Study:
- To evaluate the computed tomographic (CT) imaging features of pseudomembranous colitis (PMC).
- To determine the diagnostic utility of CT in identifying PMC.
Main Methods:
- Retrospective review of CT scans from 26 patients diagnosed with PMC.
- Analysis of bowel wall thickness, distribution of involvement, and characteristic imaging findings.
Main Results:
- Twenty-three of 26 patients exhibited abnormal bowel wall thickening, averaging 14.7 mm.
- Contrast material trapped between folds mimicked transverse bands seen on radiographs.
- Pancolonic involvement occurred in 13 cases; others showed right-sided or rectosigmoid-limited thickening.
Conclusions:
- CT imaging can suggest a diagnosis of pseudomembranous colitis (PMC) in the appropriate clinical context.
- Key CT findings include bowel wall thickening and characteristic band-like appearances.
- While not entirely specific, CT plays a supportive role in diagnosing PMC.