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Updated: Jun 12, 2026
03:01
Improved Hysteroscopic Resection of Endometrial Polyps Using 6-Fr Micro-Scissors and Forceps
Published on: August 2, 2024
Occurrence of malignancy in endometrial polyps during postmenopause
1Department of Gynaecology, Perinatology and Child Health, Sapienza University, Rome, Italy. bruno.mossa@uniroma1.it
European Journal of Gynaecological Oncology
|June 10, 2010
Summary
Malignant transformation in endometrial polyps is rare, occurring in less than 3% of postmenopausal symptomatic women. Hysteroscopy-diagnosed polyps require careful histological evaluation for malignancy risk assessment.
Area of Science:
- Gynecology
- Pathology
- Reproductive Medicine
Background:
- Endometrial polyps are common, but their malignant potential is a concern.
- Differentiating benign from malignant polyps is crucial for patient management.
Purpose of the Study:
- To determine the incidence of malignancy in endometrial polyps.
- To assess risk factors such as menopausal status and symptoms.
Main Methods:
- Retrospective analysis of 351 patients with hysteroscopy-diagnosed endometrial polyps.
- Histopathological examination of polyp biopsies.
Main Results:
- Malignancy (adenocarcinoma) was found in 7 out of 351 cases (approximately 2%).
- All malignant cases occurred in symptomatic women, with 6 postmenopausal and 1 premenopausal.
- A significant association (p < 0.001) was found between menopausal status, symptoms, and malignant lesions.
Conclusions:
- The prevalence of malignant transformation in endometrial polyps is low (< or = 2.84%).
- Postmenopausal status and symptoms are significant indicators for increased malignancy risk.
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