Quantum dots synthesis and biological applications as imaging and drug delivery systems

Semiconductor quantum dots (QDs) synthesized by metal ions and colloid stabilizers have been explored as promising probes in advanced imaging techniques, tumor diagnostic agents, and drug delivery systems. The ability to modulate QDs surface chemistry through particle--shape control, surface coating, and surface functionalization-has rendered them a valuable tool in biological sciences. The tremendous advances in nanotechnology revealed the unique properties of QD crystals in both in vitro and in vivo conditions. In this review, we summarize the recent trends in QD synthesis, surface modification, and biological applications particularly for cancer targeting and treatment.