Related Experiment Video
Updated: Jun 12, 2026
04:51
Pupillary Response as Assessment of Effective Seizure Induction by Electroconvulsive Therapy
Published on: April 11, 2019
Patient-reported outcomes measurements in epilepsy
Megan Stafford1, Sonia Gavriel, Andrew Lloyd
1United BioSource Corporation, 20 Bloomsbury Square, London, WC1A 2NS, UK. megan.stafford@unitedbiosource.com.
Expert Review of Pharmacoeconomics & Outcomes Research
|June 10, 2010
Summary
This review highlights that while various patient-reported outcome measures exist for epilepsy, assessing patient preference and satisfaction remains a challenge. More research is needed to develop valid instruments for these crucial aspects of epilepsy care.
Area of Science:
- Neurology
- Patient-Reported Outcomes
- Epilepsy Research
Background:
- Patient-reported outcomes (PROs) are crucial for understanding the impact of epilepsy on individuals.
- Existing PRO instruments primarily focus on quality of life, symptoms, and psychosocial functioning.
Purpose of the Study:
- To review and analyze the range of PRO instruments used for assessing individuals with epilepsy.
- To identify gaps in current PRO assessment tools for epilepsy patients.
Main Methods:
- Comprehensive literature searches of EMBASE.com and hand searching of relevant articles.
- Inclusion of English language papers published between January 1997 and March 2007.
- Systematic review of 61 relevant studies.
Main Results:
- Several validated PRO instruments exist for epilepsy, including Quality of Life in Epilepsy (QOLIE) and Liverpool Seizure Severity Scale.
- Specific instruments like QOLIE-adolescent are available for adolescent populations.
- A significant paucity of valid condition-specific instruments for patient preference and satisfaction was identified.
Conclusions:
- While PROs for quality of life, symptoms, and psychosocial aspects are well-developed in epilepsy, measures for patient preference and satisfaction are underdeveloped.
- Further development of PRO instruments is needed to comprehensively assess patient perspectives in epilepsy care.
Related Concept Videos
01:24Epilepsy and Seizures: Overview
Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
Various factors can trigger epilepsy, including genetic factors, brain damage, metabolic causes, and unknown etiology. Diagnosis of epilepsy involves electroencephalography (EEG), which...
01:13Seizures: Classification
Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types:
Seizures are typically classified into two main categories: focal and generalized seizures.
Focal Seizures
Focal seizures originate from specific regions of the brain. These seizures are further sub-classified into two types: