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Updated: Jun 12, 2026

FISH for Pre-implantation Genetic Diagnosis
Published on: February 23, 2011
Misconstructions in health economics applied to the evaluation of prenatal screening
1Santé Publique, Hôpital, Henri Mondor, AP-HP, 51 avenue du maréchal de Lattre de Tassigny, 94010 Créteil, France. Isabelle.durand-zaleski@hmn.aphp.fr.
Abstract:
The application of economic evaluation to prenatal screening has led to ethical debates about the joint risks of rationing and eugenics. These debates have chosen the wrong target, as economic evaluations espouse the hypotheses and value judgment of their commissioners. This paper explores the difficulties in interpreting and using the results of economic evaluations. The first set of difficulties concerns the diversity in end points and the lack of an aggregate end point to reflect a generally desirable outcome. Another set results from the wider societal implications of economic evaluations and the implicit value judgments. Misunderstandings of the methods used for the economic evaluation of prenatal screening result from the lack of clearly stated objectives from policy makers.
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