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Updated: Jun 12, 2026

Non-invasive Optical Measurement of Cerebral Metabolism and Hemodynamics in Infants
Published on: March 14, 2013
Effect of infants' position on serum bilirubin level during conventional phototherapy
M L Donneborg1, K B Knudsen, F Ebbesen
1Department of Paediatrics, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark. fe@rn.dk
Insights
Infant positioning during phototherapy for hyperbilirubinaemia does not impact total serum bilirubin (TSB) reduction. Routine position changes every three hours are common in Scandinavia but unnecessary for effective treatment.
Area of Science:
- Neonatal care
- Pediatric phototherapy
- Bilirubin metabolism
Background:
- Neonatal hyperbilirubinaemia is common.
- Phototherapy is a standard treatment.
- Infant positioning during phototherapy varies.
Purpose of the Study:
- Compare TSB reduction with exclusive supine vs. alternating supine/prone positioning.
- Survey phototherapy practices in Denmark and Norway.
Main Methods:
- 112 healthy infants with non-haemolytic hyperbilirubinaemia randomized.
- Phototherapy for 24 hours.
- TSB measured at 0, 12, and 24 hours.
- Survey of 41 neonatal departments.
Main Results:
- No significant difference in TSB decrease between positioning groups (12h: 32% in both; 24h: 49% vs 50%).
- Two-thirds of departments routinely alternate infant positions.
- Most common alternation interval is every three hours.
Conclusions:
- Infant positioning does not significantly affect TSB reduction during phototherapy.
- Widespread alternating exposure practice in Scandinavia is unnecessary.
Aim:
To compare the decrease in total serum bilirubin (TSB) concentration during conventional phototherapy in infants treated in supine position exclusively versus infants alternated between exposure in supine and prone position every third hour. Moreover, to survey current practice patterns in two Scandinavian countries as far as alternating exposure.
Methods:
A total of 112 infants with non-haemolytic hyperbilirubinaemia, but otherwise healthy, and a gestational age > or =33 weeks were randomized to one of the treatment groups. All infants received phototherapy for 24 h. TSB was measured at start of phototherapy and after 12 and 24 h of treatment. Questionnaires about routines for position changes in infants during phototherapy were sent to all 41 neonatal departments in Denmark and Norway.
Results:
No statistically significant differences in the decrease in TSB were observed between the two treatment groups: at 12 h of therapy, TSB decreased 32% in both groups and at 24 h 49% and 50%, respectively. In two-thirds of Danish and Norwegian departments, the infants were routinely turned during phototherapy, most often every third hours.
Conclusion:
The decrease in TSB was not significantly associated with positioning of the infant during conventional phototherapy. Alternating exposure is widely practiced in Scandinavia but is unnecessary.
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