Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The site of the optical image in the eye.

Medical hypotheses·2013
Same author

The entoptic view of the retinal vessels.

Acta ophthalmologica·2013
Same author

Aqueous humor dynamics in historical perspective.

Survey of ophthalmology·2009
Same author

The role of eye size in its pressure and motility.

Clinical ophthalmology (Auckland, N.Z.)·2009
Same author

On the evolution of binocular ophthalmoscopy.

Archives of ophthalmology (Chicago, Ill. : 1960)·2007
Same author

Ocular surface carcinoma.

Connecticut medicine·2006
Same journal

Distinguish polypoidal choroidal vasculopathy through choroidal alterations: A systematic review, meta-analysis and narrative synthesis.

Acta ophthalmologica·2026
Same journal

Ocular blood flow and retinal oxygen saturation measurements in central retinal artery occlusion.

Acta ophthalmologica·2026
Same journal

Retinal dystrophies simulating geographic atrophy: A diagnostic challenge.

Acta ophthalmologica·2026
Same journal

Radial outer retina reflectivity (RORR) sign in LAMP2-associated retinopathy.

Acta ophthalmologica·2026
Same journal

Deep learning in glaucoma referral: Performance assessment using a real-world setting.

Acta ophthalmologica·2026
Same journal

Clinical manifestations of dual-gene variants in retinitis pigmentosa.

Acta ophthalmologica·2026
See all related articles

Related Experiment Video

Updated: Jun 12, 2026

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Buphthalmos: early glaucoma history.

Harry H Mark1

  • 1Yale-New Haven Hospital, North Haven, CT 06473, USA. iimd@aol.com

Acta Ophthalmologica
|June 10, 2010
PubMed
Summary
This summary is machine-generated.

Buphthalmos, a form of glaucoma causing enlarged eyes, was recognized in antiquity. Modern glaucoma detection, relying on optic nerve examination and intraocular pressure measurement, began in the mid-19th century.

More Related Videos

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
13:47

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

Related Experiment Videos

Last Updated: Jun 12, 2026

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Ultrasound Cyclo Plasty in Eyes with Glaucoma
05:05

Ultrasound Cyclo Plasty in Eyes with Glaucoma

Published on: January 26, 2018

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis
13:47

Laser Capture Microdissection of Highly Pure Trabecular Meshwork from Mouse Eyes for Gene Expression Analysis

Published on: June 3, 2018

Area of Science:

  • Ophthalmology
  • Medical History

Background:

  • Modern glaucoma diagnosis relies on optic nerve visualization and intraocular pressure measurement, developed post-1850s.
  • Buphthalmos, a distinct glaucoma presentation, has been recognized since ancient times due to its visible ocular enlargement.

Observation:

  • The article examines the historical understanding of buphthalmos, including its nomenclature, clinical signs, and therapeutic interventions.
  • This historical review spans from ancient Greek medical texts to the mid-19th century.

Findings:

  • Ancient recognition of buphthalmos was limited to cases with observable globe enlargement.
  • The development of specialized instruments in the mid-19th century revolutionized glaucoma detection and understanding.

Implications:

  • Understanding historical perspectives on buphthalmos provides context for the evolution of glaucoma diagnosis and treatment.
  • The study highlights the impact of technological advancements on medical diagnostic capabilities.