Related Experiment Video
Updated: Jun 12, 2026

5/6 Nephrectomy Using Sharp Bipolectomy Via Midline Laparotomy in Rats
Published on: April 4, 2025
How ready is general practice to improve quality in chronic kidney disease? A diagnostic analysis
Iain Crinson1, Hugh Gallagher, Nicola Thomas
1St Georges, University of London, London.
Insights
Practitioners hold varied views on chronic kidney disease (CKD) management, questioning its definition and treatment targets. Educational support is crucial for implementing CKD guidelines effectively.
Area of Science:
- Nephrology
- Primary Care Medicine
- Health Services Research
Background:
- Chronic kidney disease (CKD) significantly increases cardiovascular risks and renal failure progression.
- Primary care interventions, especially blood pressure control in patients with CKD, proteinuria, and diabetes, can slow disease advancement.
- National guidelines and pay-for-performance targets aim to standardize CKD management.
Purpose of the Study:
- To investigate healthcare practitioners' perceptions and understanding of chronic kidney disease (CKD) and its management strategies.
- To inform the development of quality-improvement interventions for CKD care.
Main Methods:
- Qualitative study employing focus groups across five English locations.
- Standardized facilitation approach with data analysis using the 'framework' method.
Main Results:
- Practitioners expressed diverse opinions on CKD, with some adhering to full guidelines and others focusing solely on pay-for-performance targets.
- Widespread skepticism existed regarding CKD as a distinct disease, its diagnosis based solely on estimated glomerular filtration rate, and its relevance in older adults.
- Difficulties were reported in communicating CKD to patients, alongside challenges and skepticism concerning blood pressure targets, indicating educational gaps.
Conclusions:
- Significant variation exists in practitioners' understanding and approach to CKD management.
- Future quality-improvement interventions, such as the QICKD study, must integrate substantial educational components.
- The implementation of CKD guidelines may have been hampered by insufficient educational support for practitioners.
Background:
Chronic kidney disease (CKD) is associated with increased cardiovascular mortality and morbidity as well as progression to established renal failure. Interventions in primary care, particularly the lowering of blood pressure in individuals with CKD and proteinuria and diabetes, can slow disease progression. This evidence base is codified in national guidance and in a simplified form in pay-for-performance targets. Prior to conducting the QICKD study - a cluster of quality-improvement interventions with reduction of blood pressure as its primary outcome measure - a diagnostic analysis was conducted to assess the relevance of the intended interventions.
Aim:
To understand practitioners' views of CKD and its management.
Method:
Focus groups were held in five locations across England. Experienced facilitators developed a standardised approach and analysed data using the 'framework' approach.
Results:
Practitioners varied in their views of CKD and their embracing of the guidance. Some sought to implement the full guidance, others only the pay-for-performance targets. Nearly all practitioners had reservations as to whether CKD was really a disease; problematised the diagnosis of CKD purely on an estimate of glomerular filtration rate; questioned whether CKD in older people was part of natural ageing; and had experienced difficulty in explaining the condition to patients without frightening them. Most reported both problems and scepticism concerning the blood pressure targets, and acknowledged educational gaps.
Conclusion:
Practitioners have disparate views about CKD. The quality-improvement interventions in the QICKD study will need to incorporate a large element of education. CKD guidelines may have been introduced without sufficient educational support.
Related Concept Videos
Chronic Kidney Disease III: Interprofessional Care
Chronic Kidney Disease I: Introduction
Chronic Kidney Disease IV: Nursing Management
Acute Kidney Injury IV: Diagnostic Studies and Prevention
Chronic Kidney Disease II: Clinical Manifestations
Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...

