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Related Experiment Video

Updated: Jun 12, 2026

Laparoscopic Common Bile Duct Exploration in Patients with a Previous History of Biliary Tract Surgery
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Laparoscopic Common Bile Duct Exploration in Patients with a Previous History of Biliary Tract Surgery

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Laparoscopic cholecystectomy with Harmonic scalpel.

Roberta Gelmini1, Chiara Franzoni, Stefano Zona

  • 1Department of Surgery, Policlinico of Modena, University of Modena and Reggio Emilia, Italy. roberta.gelmini@unimore.it

JSLS : Journal of the Society of Laparoendoscopic Surgeons
|June 10, 2010
PubMed
Summary

The Harmonic scalpel offers a safe alternative for laparoscopic cholecystectomy, reducing operative time without increasing complications. This ultrasonic device provides effective dissection and vessel sealing, potentially lowering costs.

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Area of Science:

  • Minimally Invasive Surgery
  • Surgical Technology

Background:

  • Laparoscopic cholecystectomy is standard for gallstones.
  • Monopolar hook use carries risks like thermal injury and biliary complications.
  • Ultrasonically activated scalpels, like the Harmonic, are increasingly used to mitigate these risks.

Purpose of the Study:

  • To compare the Harmonic scalpel with monopolar electrosurgery for laparoscopic cholecystectomy.
  • To evaluate safety, efficacy, and operative time.

Main Methods:

  • A 2-year study of 95 patients using the Harmonic scalpel as the sole instrument.
  • Comparison with a control group using monopolar electrosurgery and clips.
  • Analysis of inpatient stay, procedure duration, and complications.

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Last Updated: Jun 12, 2026

Laparoscopic Common Bile Duct Exploration in Patients with a Previous History of Biliary Tract Surgery
07:36

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Published on: February 10, 2023

Laparoscopic Cholecystectomy with Indocyanine Green Fluorescence: Choledochoscopic Stone Extraction and Primary Duct Suture
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Published on: November 25, 2025

Main Results:

  • No significant difference in major complications or bile duct injuries between groups.
  • Mean operative time was significantly shorter with the Harmonic scalpel.
  • No statistically significant difference in postoperative complications.

Conclusions:

  • The Harmonic scalpel is a safe, effective, and reliable alternative to clips for achieving hemobiliary stasis.
  • It offers advantages of shorter operation time and potential cost savings.
  • Represents a viable alternative for laparoscopic cholecystectomy.