Related Experiment Video
Updated: Jun 12, 2026

Coronary Progenitor Cells and Soluble Biomarkers in Cardiovascular Prognosis after Coronary Angioplasty
Published on: January 28, 2020
Early diagnostic markers for contrast nephropathy in patients undergoing coronary angiography
Olfat G Shaker1, Amal El-Shehaby, Mohamed El-Khatib
1Department of Medical Biochemistry, Faculty of Medicine, Cairo University, Egypt. olfatshaker@yahoo.com
Unlabelled:
The present work aimed to prove the usage of neutrophil gelatinase-associated lipocalin (NGAL) as an early biomarker for kidney injury and to assess the relationship between NGAL and serum creatinine and cystatin C in patients with normal serum creatinine undergoing percutaneous coronary angiography. Thirty patients with normal serum creatinine undergoing coronary angiography were enrolled. Estimation of blood glucose, glycosylated hemoglobin, lipid profile, creatinine, NGAL, and cystatin C were done before coronary angiography for all patients. Serum creatinine, NGAL and cystatin C were evaluated again at 4 and 24 hours after coronary angiography. There was a significant increase in serum NGAL level 4 hours and 24 hours after coronary interventions compared to the baseline value before coronary angiography. Before coronary angiography, serum NGAL was positively correlated with serum creatinine, and cystatin C.
Conclusion:
Serum NGAL and cystatin C could be valuable in the detection of early renal impairment after coronary angiography.
Related Concept Videos
Acute Coronary Syndrome III: Diagnostic Studies
Imaging Studies for Cardiovascular System V: CT
Cardiac Catheterization I: Pre-Procedure Overview
Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
Blood Studies for Cardiovascular System II: CRP, Hcy, and Cardiac Natriuretic Peptide Markers
These markers indicate stress or strain on the heart muscle:
Natriuretic Peptides (BNP)
Cardiac myocytes produce these hormones in response to ventricular stretching...
Imaging Studies VII: Vascular Imaging

